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Tissues COPY Flashcards

1
Q

List examples of how hormones can cause problems in the hair

A

slide 28-32

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2
Q

Describe what an organelle and what a eukaryotic organism is.

A

tissues, word ,pg 1

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3
Q
  1. Review the structure and function of the major organelles in cells
A

tissues, word ,pg 1

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4
Q

plit the cytoskeleton into its main components and describe the functions of the main cytoskeletal components

A

tissues, word ,pg1

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5
Q

Some of the main cytoskeletal components have their actions in a particular part of the cell compared to others, identify the components and where their actions are

A

tissues, word ,pg 2

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6
Q

The components of the cytoskeleton are not fixed. They are dynamic and subject to rapid

remodelling using biochemical and biomechanical signals

(T/F)

A

tissues, word ,True

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7
Q

State the mian cell types and describe their features, and describe their name of their corresponding tumours

A

tissues, word ,pg 3

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8
Q

Do epithelial tissue line internal or external surfaces. List their functions here ,and explain the features they have that aid these functions.

A

tissues, word ,pg 4

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9
Q

Describe the features and fiunctions of the different types of cell to cell junctions

A

tissues, word ,pg 5

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10
Q

Explain the labile feature of cell to cell junctios

A

tissues, word ,pg 5

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11
Q
  1. Describe the classification of epithelia
A

tissues, word ,pg 7

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12
Q

Give the real life human tissue examples of the epithelial classifications

A

tissues, word ,pg 7

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13
Q
  1. Describe** **the** **role** **ofcell-­‐‑celljunctionsinepithelialpolarity
A

tissues, word ,pg 7

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14
Q

For particular examples of types of epithelia describe the role of polarity and additional features of component separation of the cytoplasmic domains that aid function

A

tissues, word ,pg 9

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15
Q
  1. Describe the relationships between cellular organisation and epithelial function
A

tissues, word ,pg 11

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16
Q

How is the epithelium arranged intissues where the main purpose is secretion

A

tissues, word ,pg 11

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17
Q

Recall difference between constitutive and stimulated secretion

A

tissues, word ,pg 11

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18
Q

Descrube the structure of the skin and Explain how problems could occur in the skin

A

tissues, word ,pg 12

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19
Q
  1. Describe patterns of cell division in the turnover of epithelia
A

tissues, word ,pg 12

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20
Q

Describe the functions of the extracellular matrix

A

tissues, word ,pg 13

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21
Q

Describe the components of connective tissues, and the component of the basal lamina below the epithelial sheet

A

tissues, word ,pg 13

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22
Q

Describe the pathgenesis of Human disorders from ECM abnormalities

A

tissues, word ,pg 15

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23
Q

which proteins are the most abundant in mammals and what is this proportion)

A

tissues, word ,pg 15

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24
Q

where are collagens major proteins)

A

tissues, word ,pg 15

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25
Q

Describe the possible ways collagen fibrils can be arranged

A

tissues, word ,pg 15

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26
Q

How many different types of collagen are known).

A

tissues, word ,pg 15

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27
Q

Describe the difference between type 1 collagens and type 2 and 3 collagens

A

tissues, word ,pg 15

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28
Q

how many genes code for collagen

A

tissues, word ,pg 15

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29
Q

Describe the general structure of a collagen alpha chain

A

tissues, word ,pg 16

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30
Q

Describe Collagen biosynthesis

A

tissues, word ,pg 16

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31
Q

Explain the pathogenesis of scurvy

A

tissues, word ,pg 18

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32
Q

Are any cross links formed after secretion

A

tissues, word ,pg 18

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33
Q

Are any cross links formed after secretion

A

tissues, word ,pg 18

34
Q

Describe the arrangement of collagen fibrils in different tissues and the consequences of such arrangements

A

tissues, word ,pg 18

35
Q

Describe the roles of non-fibrillar collagens and identify which type are non-fibrillar

A

tissues, word ,pg 18

36
Q

Descrube the role and structure of elastic fibres

A

tissues, word ,pg 19

37
Q

Describe the structure of Elastin

A

tissues, word ,pg 19

38
Q

Describe the composistion , structure , location and significance of the Basement membranes (Basal laminae)

A

tissues, word ,pg 21

39
Q

Describe what laminins are , their structure , location and functions. Also, provide give details of pathologies associated with them.

A

tissues, word ,pg 22

40
Q

Describe the structure function and genetic associations of fibronectin

A

tissues, word ,pg 22

41
Q

What are proteoglycans , describe their structure and the consequences of these structures. Give the details of the different proteoglycan families. Must include all important details of GAGs)

A

tissues, word ,pg 24

42
Q

describe the difference between small and large proteoglycans

A

tissues, word ,pg 25

43
Q

State the four main groups of GAG

A

tissues, word ,pg 25

44
Q

Describe the structure of Hyaluronin, how it is secreted

A

tissues, word ,pg 25

45
Q

How is a GAG bound to the core protein

A

tissues, word ,pg 25

46
Q

Describe the structure of dermatan sulphate and chondroitin sulphate

A

tissues, word ,pg 26

47
Q

Describe the structure and importance of decorin

A

tissues, word ,pg 27

48
Q

Describe agragan structurere

A

tissues, word ,pg 28

49
Q

Describe the feature s of hylaine cartilage

A

tissues, word ,pg 28

50
Q

Explain the pathogenesis of osteoarthritis

A

tissues, word ,pg 29

51
Q

Decsribe Fibrotic disorders pathogenesis

A

tissues, word ,pg 29

52
Q
  1. Recall: the Size and composition of fluid compartments-check brackets for rest
A

tissues, word ,pg 30

53
Q

describe the difference in protein content between plasma and interstitium

A

tissues, word ,pg 30

54
Q

Describe what is significant about Ca2+ concentrations intracellularly abnd extracellularly

A

tissues, word ,pg 30

55
Q

Decsribe the features of protein anions

A

tissues, word ,pg 31

56
Q

Exaplain and Differentiate between tonicity and osmolarity, and use scenarios to describe the different circumstances where they have an effect of the cell .

A

tissues, word ,pg 31

57
Q

what is the osmolarity of 150mmol/L of NaCl)

A

tissues, word ,pg 31

58
Q

role of Na/K pump in prevent consequences of tonicity

A

tissues, word ,pg 31

59
Q

Describe the different forms of Transport across membranes

A

tissues, word ,pg 31

60
Q

Describe Exchange across capillary wall, and pathogenesis of disorders associated with it.

A

tissues, word ,pg 32

61
Q

“List cell types within the nervous system and 2) recall their functions.”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

tissues, ,pg 162 ibook

62
Q

“Explain processes of intercellular communication.”

A
  • tissues, ,pg 164 i-165 book
63
Q

“ Recall the components of a neurone.”

A

,pg 162 ibook under neurones

64
Q

“Explain how function is conveyed by generation of the resting membrane potential.”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

tissuee ,pg 166 ibook

65
Q

“ recall the ultrastructure of skeletal muscle, list functional characteristics, explain the process of excitation-contraction coupling and the cellular mechanisms resulting in contraction.”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

ibook, Muscle

66
Q

“Cardiac muscle: explain the structure, physiology and function of cardiac muscle, and compare with skeletal muscle.”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

ibook , muscle

67
Q

“ explain the structure, physiology and function of smooth muscle, and compare with striated muscle.
”

A

ibook , muscle

68
Q

“Explain the concept of the skin as a single organ of the body, with its complex inter-relationships with other organ systems”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

skin , ibook

69
Q

“Summarise the functions of skin”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

ibook , skin

70
Q

“Outline the basic structure of the skin and the relationships between the epidermis, dermis and subcutaneous layer (subcutis)”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

skin, ibook

71
Q

“Outline the mechanisms by which the integrity of the dermo-epidermal junction is maintained”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

skin,ibook

72
Q

“Explain the development, function and control of melanocytes and their role in skin pigmentation”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

skin,ibook

73
Q

“Summarise the functions of hair, and recall the different types”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

Hair and Nails, ibook

74
Q

“Explain the development of the hair follicle and its structure”

A

ibook, Hair and Nails

75
Q

“Summarise the functions, structure and growth of finger and toe nails”

Excerpt From: Imperial College London. “MBBS Year 1 MCD Autumn 17/18.” iBooks.

A

ibook , HAir and nails

77
Q

1.Explain the physiological functions of cell signalling and list examples of intercellular siganlling

78
Q

1.Explain, with examples, modes of intercellular signalling including, endocrine, paracrine, autocrine, and signalling by membrane attached proteins

79
Q

1.list examples of intracellular signalling

80
Q

1.Signal transduction pathways: explain the transmission of an extracellular signal within a cell and recall physiological examples

MCD (40 decks)

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