Microbiology COPY Flashcards
Recall the details of a generic virus replication cycle
Give two examples of viruses whose tropism are determined by receptor use)
List the features that infectious dose is affected by
Laz’s notes,138
- Describe the** **Consequences of infection via the GI tract
Laz’s notes,136
Describe the distribution of serious fungal infections of humans in terms of their phyla
Laz’s notes ,150
define subcutaneous mycoses
Laz’s notes ,153
Recall the difference bwetween vertical and horizontal DNA transmission
Vertical DNA transmission
Hand transmission can act as an intermediate for Portal of Entry - Upper Respiratory Tract(True/False)
Laz’s notes ,T,134
the SMALL INTESTINE you get GRAM NEGATIVE BACTERIA and gram positive bacteria(True/False)
Laz’s notes ,F, the SMALL INTESTINE you only get GRAM NEGATIVE BACTERIA,134
List the properties of a good vaccine, and describe the features of two of these properties
Explain the concept of latency, using the example of the Herpes Simplex Virus to illustrate your answer
Define PATHOGENICITY ISLAND
Laz’s notes,133
Explain the concept of antigenic drift
Describe the mechanism of action of seven antibiotic sub-groups
Laz’s notes,142
Use two examples to illustrate how Genetic Resistance and Susceptibility may affect outcome of virus infection
What is a mycose
Laz’s notes ,151
List the different techniques following gram stain that may be used to distinguish between bacteria
pg 128 Laz’s notes
- What is involved in the new strategy for influenza vaccination in children(2)
Define resistance , breakpoint and minimum inhibitory concentration
Laz’s notes,141
what is the treatment for mycotoxicosis
Laz’s notes,151
Describe what happens in the four stages of vaccine clinical trials
Define active and passive immunity and state the purpose of a vaccine
Recall features of the tetanus and diphtheria toxin, and how the toxoid used for them is produced.
RECALL THE DIFFERENT TYPES OF HIV Treatment
How does papillomaviruses cause cancer
Describe the process of Attenuation of Viruses to make Live Virus Vaccines
Postulate possible consequences of infections with EBV
Describe the the Replication Cycle of HIV-1
Describe what superficial mycoses are and give examples of them.
Laz’s notes,152
Analyse 3 examples of a pathogens that has a feature that increases it virulence
Laz’s notes ,137
List features that enhance virulence
Laz’s notes,137
Name an example of what Cell mediated immunity would be important for
Describe the defining feature of a retrovirus
State two methods bacteria may use to get into a host cell(129-130)
Laz’s notes,(129-130)
How main phyla does the fungi kingdom consist of and what are the names of these phyla
Laz’s notes,150
Give examples of attenuated vaccines
Name four mechanisms of antibiotic resistance:
Laz’s notes ,145
Describe what cutaneous mycoses are( double check info here) and give examples of them.
Laz’s notes,152
Describe how the action of viruses can be investigated in the labarotary and explain the usual results viewed once viruses are investigated.
- Describe the Three Main Mechanisms for horizontal gene transmission:
Laz’s notes ,132
List and describe some of the features of the different categories of antigenic properties of vaccines(not sure about this one)
Name the viruses,bacteria and the toxins for Portal of Entry: The Gastro-Intestinal Tract (‘faeco-oral route’)
Laz’s notes,136
Name** **Three Types of Illness caused by Fungi
Laz’s notes ,150
Use two examples to illustrate how Co-Infections
may affect outcome of virus infection
What is significant about of the consequences of listeria infection via the GI tract
Laz’s notes,137
Summarise the consequences of the Viral Genome Type
Explain what is included in Vaccine Formulations
Describe the full details as to how structures as sophisticated as those involved in the invasion of host cells have evolved, include statistical evidence for these details?
Laz’s notes ,131
Describe Non-immune mechanisms for host defence against infectious agents
Outcome of infection can vary depending on(state seven
How do conjugate vaccines work
How can people who exposed to HIV not be affected by the virus and describe how this can change in HIV replication
What is needed to acquire an infection through the skin, give examples of causes of broken skin.
Laz’s notes,135
Explain how Inactivation of Antibiotic can act as a mechanism for antibiotic resistance and give examples of when this can happen
Laz’s notes,146
There is a vaccine for HBV and HCV(T/F)
There is a vaccine for HBV and no vaccine for HCV
- influenza evolves fast(why must influenza vaccine be regularly updated)
describe the role of adjuvants)
The majority of bacteria are harmless or beneficial (COMMENSAL), but some are pathogenic(True/False)
Laz’s notes, pg 128, True
DESCRIBE THE EPIDEMIOLOGY OF INVASIVE ASPERGILLOSIS
Laz’s notes,154
(give an example of virus whose tropism is not determined by receptor use)
Name an example of what humoral immunity would be important for
Describe the features of the Shingles Vaccine, how it is used and why
what causes hepatocellular carcinoma
Describe the functions of flagella and Type III Secretion System
Laz’s notes,pg 130
Recall examples ofSubunit Vaccines
Explain how Decreased Drug Accumulation can act as a mechanism for antibiotic resistance and give examples of when this can happen
Laz’s notes ,146
Describe the process of Making recombinant attenuated virus vaccines
Explain the general categorisation of adjuvants
A good vaccine PROVIDES SUBSTANTIAL BENEFIT TO HEALTH AT LOW COST AND LOW RISK(True/False)
T
DESCRIBE THE METHOD OF Diagnosis of Fungal Infections
Laz’s notes,155
Recall the different methods that can be used for
Hepatitis C Treatment
What is the name of the typhoid vaccine- describe how it is produced
what is a mycetoma
Laz’s notes,153
Which cell type does the Epstein Barr Virus most commonly affect, and what are symptoms-what is the genric name for the symtomes?
Name two examples of successful virus vaccination and describe why one of them is successful
(in what scenario would herd immunity be irrelevant
Resistance to AB usually arises soon after the introduction of AB to clinical use in hospitals.(State two exceptions to this rule and explain one of these exceptions)
Laz’s notes,141
)Summarise how you can get Viral Rashes
Using an example, illustrate how Viral Load may affect outcome of virus infection
Explain the TWO Strategies to Inhibit Influenza
explain what a quasi species is
Describe the features of a killed whole cell vaccine
Describe and explain two examples of the manipulation of actin by bacteria, and identify the kind of bacteria that use such
Laz’s notes,131
Explain the use of gram staining to identify bacteria
pg 127 laz;s notes
Summarise the different ways of the joint process of transcription and translation in viruses
Recall the equation for calculating the herd effect
For portal of Entry - Urogenital Tract,dissect the sources of bacteria and name the bacteria that go through these sources
Laz’s notes,135
Give examples of intra and extracellular bacteria
Laz’s notes, pg 129
Horizontal gene transfer allows the rapid spread of antibiotic resistance (T/F)
Laz’s notes,149
where is vaccine efficacy determined
HBV is a hepadnavirus (has a DNA genome) but it uses reverse transcriptase during a stage in its life cycle (T/F)
T
Recall the ways of describing the patterns of viral infection, and what they mean
why must influenza vaccine be regularly updated)