Thrombosis: A Case Study 07.11.23

Question 1

What are the 3 stages of the coagulation cascade

Answer 1

Vasoconstriction, Primary haemostatis, secondary haemostasis

Question 2

What are the 3 coagulation cascades?

Answer 2

Extrinsic pathway, intrinsic factor, common pathway/coagulation cascade

Question 3

Extrinsic and intrinsic pathways lead to the final common pathway by activating which factor?

Answer 3

Factor X

Question 4

What is extrinsic pathway activated by?

Answer 4

Tissue factor/factor VII interaction with calcium

Begins when tissue is exposed to blood

Question 5

What is the intrinsic factor activated by?

Answer 5

Begins when factor XII exposed to collagen (activated by factors in the blood)

Factors XII, XI, IX, VIII

Question 6

What factors are involved in the coagulation cascade?

Answer 6

Factors X, V, II, I, XIII

Question 7

Ultimately what does the coagulation cascade convert …… into…….

Answer 7

Ultimately converts fibrinogen (I) to fibrin

Question 8

Learn the coag pathways

Question 9

Where do clotting factors come from?

Answer 9

Liver

Question 10

Learn verkovs triad