Things I've Gotten Wrong Flashcards
MC cause of acute pericarditis
Idiopathic
OR
Viral (coxsackie and echovirus)
High pitched 3rd heart sound, dyspnea, and signs of right sided heart failure should make you think of this…
Constructive pericarditis
Describe a pericardial knock
High pitched 3rd heart sound that occurs due to sudden cessation of diastolic filling
Tx for constructive pericarditis
Pericardectomy
MC cause of myocarditis
Viral or postviral immune mediated damage
What causes rheumatic fever?
Acute autoimmune reaction to group A beta-hemolytic strep
Jones criteria for rheumatic fever
MAJOR Migratory polyarthritis Active carditis Subcutaneous nodules Sydenham’s chorea Erythema marginatum
MINOR Fever Joint pain Increased phase reactants Prolonged PR
Tx for rheumatic fever
2-6wk Aspirin taper
Pen G
MC cause of mitral stenosis
Rheumatic heart disease
MC causative organism of infective endocarditis
Subacute course: strep virus and from oral flora
Acute course or IVDU: staph aureus
*consider enterococcus in men who had recent GI/GU procedure
4 peripheral manifestations of infective endocarditis
Janeway lesions
Roth spots
Osler nodes
Splinter hemorrhages
Tx of endocarditis
Acute native: nafcillin with gentamicin for 4-6wk
Suspect MRSA, pcn allergic, or IVDU: vancomycin with gentamicin
Prosthetic valve: vanco, genta, and rifampin
Fungal: ampho B
Endocarditis prophylaxis indications and tx
- Prosthetic valve
- Prosthetic repairs
- Hx of endocarditis
- Congenital heart dz
- Valvulopathy of transplanted heart
2g amoxicillin or if pcn allergic 600mg clinda
DVT treatment duration
1st episode with recent surg, transient identifiable factor, or high bleed risk: 3mo
Idiopathic 1st episode: 6mo
Recurrent episode:1yr
Left bundle branch block
- wide QRS
- Slurred R is V5-6
- Deep S in V1
- possible ST elevations in V1-3
Where is the infarct: ischemic changes in V1-4?
anterior wall
LAD
Where is the infarct: ischemic changes in V1-2?
Septal
Proximal LAD
Where is the infarct: ischemic changes in I, aVL, and V5-6?
Lateral wall
Circumflex
Where is the infarct: ischemic changes in I, aVL, and V4-6?
Anterolateral wall
Mid LAD or circumflex
Where is the infarct: ischemic changes in II, III, and aVF?
Inferior wall
Right coronary artery
Where is the infarct: ST DEPRESSION in V1-2?
Posterior wall
right coronary artery or circumflex
1st line tx for WPW syndrome
Procainamide
Antiarrhythmic classes
Class I-Na channel blockers/rhythm: procainamide, lidocaine, flecanude
Class II-beta blockers/rate: atenolol, metoprolol, esmolol, ect
Class III- K channel blockers/rhythm: amiodarone, dofetilide, sotalol
Class IV-Ca channel blockers/rate: verapamil, diltiazem
Class V-digoxin
Asthma classification by FEV1
Intermittent: >80%
Mild persistent: >80%
Moderate persistent: 60-80%
Severe persistent: <60%
PFTs in COPD
FEV1/FVC is <70%
In emphysema also look for increased lung volumes and decreased DLCO
Tram track appearance on chest CT, with chronic cough, mucopurulent sputum and hemoptysis
Bronchiectasis
Tx of bronchiectasis
ABX
MC cause of bronchiectasis
Recurrent infections - H flu
Pseudomonas in CF patients
Gram negative rod causing pneumonia with cavitary lesions in an alcoholic
Klebsiella
Gram negative rod causing CAP in pt with underlying lung dz
H flu
Gram positive cocci in pairs that is MC cause of CAP
Strep pneumo
Intracellular gram negative rod that causes atypical pneumonia with GI sx, hyponatremia, and elevated LFTs
Legionella
Gram positive cocci in clusters that often causes multilobular pneumonia after a viral illness
Strap aureus
MC viral cause of pneumonia
RSV & parainfluenza in infants and children
Influenza in adults
Pneumonia associated with bird/bat droppings in Ohio/Mississippi river valley
Histoplasmosis
Causative agent of bullous myringitis
Mycoplasma
Pneumonia treatment
CAP outpt: clarithro, azithromycin, or doxy
Inpt or ICU: add FQ or beta lactam
Hospital acquired: consider pseudomonas coverage, vanco or linezolid if MRSA, and Levi or azithro if legionella
Restrictive lung dz PFTs
Decreased lung volumes with
Normal or increased FEV1/FVC
Tx of active TB infection
4drug regiment for 2mo followed by 4mo of dual therapy
Rifampin, isoniazid, pyrazinamide, and ethambutol (or streptomycin)
RIPE or RIPS
Rifampin MOA and adverse effects
Inhibits RNA synthesis
Thrombocytopenia and orange secretions
Isoniazid MOA and adverse effects
Inhibits mycolic acid synthesis
Hepatitis, peripheral neuropathy (give B6 pyridoxine), rash
Pyrazinamide adverse effects and cautions
Hepatitis, hyperuricemia, and photosensitivity
Caution in gout or liver dz
Ethambutol adverse effects
Optic neuritis
Peripheral neuropathy
Latent TB infection tx
Isoniazid with B6 for 9-12mo
MC cause of acute bronchitis
Often follows viral URI
Tx of Whooping cough
Supportive tx
Erythromycin or azithromycin can be considered or given to exposed contacts
*bactrim if macrolide allergic
Who gets acute bronchiolitis and what is the MC cause?
Children 2mo to 2yr old
After viral infection
RSV mainstay of tx
Humidified O2
*ribavirin only in severe cases
MC cause of croup(laryngotracheitis)
Parainfluenza
Compare Chet-Stokes with Biot’s breathing.
Cheyenne-Stokes have a regular cycle of decreased breathing leading to apnea
BUT
Biot’s breathing is iregular quick shallow breaths with irregular periods of apnea
Normal values for determining acid-base disorders
pH >7.45 alkalosis
pH <7.35 Acidosis
Pco2 35-45
HCO3 22-26
Delta waves should make you think of
WPW syndrome
U waves should make you think of
Hypokalemia
Quinidine
Procainamide
Flaccid bulla with positive Nikolsky sign
Pemphigus vulagris
High riding humeral head on AP radiography
Suggestive of rotator cuff athropathy
How do you assess the murmur from a ventricular septal defect?
The louder it is the smaller the defect so the better the prognosis
What hormone replacement therapy should you recommend for menopause?
Uterus intact: estrogen/progesterone
Post hype rectory: estrogen only
Idiopathic diabetes insipidus etiology and treatment
Destruction of hypothalamus; genetic form is autosomal dominant
DOC is desmopressin
How does hyperaldosteronism affect blood pressure and lytes?
Hypertension
Hypokalemia
MC cause of hyperaldosteronism
90% are primary hyperaldosteronism due to aldosterone producing tumor or bilateral adrenal hyperplasia
How do you get toxoplasmosis?
Eating undercooked meat or changing kitty litter
TB treatment for pregnancy
Isoniazid, rifampin, and ethambutol
Streptomycin C/I and risk of pyrazinamide unkn
What triggers preeclampsia?
Placental ischemia
MC long term complication of supracondylar fracture
Cubitis varus
How do you diagnose RVS?
Nasopharyngeal swab
Medications useful for anger in borderline personality disorder
Topirimate and lamotrigine
How do you differentiate night terrors from nightmares?
Night terrors: first 60-90 minutes of sleep and associated with mental illness
Nightmares: occur during REM sleep early in the morning
DOC for TCA poisoning (ventricular arrhythmias and hypotension)
Sodium bicarbonate
How do amphetamines work?
Causing the release of dopamine and NE
Crescent sign on hip x-ray
Avascular necrosis of the hip
*a common complication following traumatic hip dislocation
Morphology and staining of strep meningitidis
Gram negative diplococcus
When is HIV PCP prophylaxis indicates?
CD4 <200
Hx PCP infection
Evidence of immunocompromise (candidiasis)
Primary treatment of tumor lysis syndrome
Aggressive rehydration
Harsh bark-like cough with wheezing since infancy should make you think of this
Tracheomalacia
Afebrile infant with staccato cough and eosinophilia should make you think of
Chlamydia trachomatis
*patchy infiltrates on CXR
Blood test for presymptomatic MEN2 associated cancers
RET mutation
Aspergilloma can be a late complication of this disease
TB
Brochilithiasis can be a late complication of this disease
Histoplasmosis
Kernig sign indicates
Meningeal irritation
Kussmauls sign indicates
Cardiac tamponade
Quick’s sign/pulse indicates
Aortic insufficiency
Newborn conjunctivitis based on time
2-5d Gono
5-14d chlamydia
First line treatment for endometritis
Clinda and genta
Post C-section fever, soft tender uterus, and foul lochia
Endometritis
10-20% pts with CLL develops this
A secondary malignancy
Urine casts
Waxy-chronic dz or vigorous exercise
Fatty-nephrotic syndrome
RBC-glomerulonephritis
WBC- pyelo or acute interstitial nephritis
Hyaline- diuretic use
Stages of Lyme disease
Early localized- rash malaise & myalgiaS
Early disseminated-heart and nervous system involvement
Late/persistent- neuropsych manifestations and joint pain
Inheritance pattern of hemophillia A and B
X linked recessive
Only boys will have it
This immunoglobulin is elevated in Waldenstrom’s macroglobinemia
IgM
This immunoglobulin is elevated in multiple myeloma
IgG
VAP associated bacteria
Pseudomonas
Klebsiella
Enterobacter
Serratia
Acinetobactor
Tx of Hodgkin lymphoma
Doxrubicine, bleomycin, vinbkastine, and dacarbazine
With possible radiation
Tx of multiple myeloma
Lenalidomide and prednisone
Who do you consult for drainage of a retropharyngeal abscess?
Otolaryngologist
What is telogen effluvium?
Stress induced hair loss