Thiazide, Thiazide-like Diuretics Flashcards

1
Q

name a thiazide diuretic

A

bendroflumethiazide

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2
Q

name tow thiazide-like diuretics

A

chlotalidone

indapamine

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3
Q

what do they target?

A

thiazide sensitive NA/Cl co-transporter in DCT

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4
Q

agonist/antagonist?

A

inhibitor

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5
Q

what do they do ?

A

reduces Na+ and Cl- reabsorption
removal of salt
VASODILATION

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6
Q

what are they used for?

A

hypertension 3rd line

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7
Q

adverse effects?

A
oto and nephrotoxicity 
hypotension
decreased: 
Na
K

increased:
Ca
pH
Urea

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8
Q

prescribing advice

A
eGFR >30
NOT with aminoglycoside antibiotics
NOT NSAIDS
NOT lithium
NOT SSRI
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