Angiotensin recpetor blockers (ARBs) Flashcards
1
Q
what do angiotensin receptor blockers end in?
A
sartan
2
Q
name two angiotensin receptor blockers
A
valsartan
losartan
3
Q
what do they target?
A
AT1 receptor
4
Q
agonist/antagonist?
A
antagonist
5
Q
how do they work?
A
prevent action of angiotensin 11 on AT1 receptors
6
Q
overall effect?
A
reduces vasoconstriction
reduces Na+/H2O retention at PCT
7
Q
when do you use it ?
A
hypertension intolerant of ACE-I
type 2 diabetes nephropathy
8
Q
prescribing advice
A
NOT with ACE-I