Theme 3 Quiz Flashcards

1
Q

Protein that is able to form pores in the membrane of infected cells? (8)

A

Perforin

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2
Q

A granuloma is a focus of chronic inflammation that consists of activated epithelioid _____
surrounded by lymphocytes and occasional plasma cells (11)

A

Macrophages

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3
Q

Example of a primary granulomatous disease that affects the intestines (6)

A

Crohns

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4
Q

A hypersensitivity reaction resulting from the injection of an antigen into a previously sensitised
animal is called the ____ reaction (6)

A

Arthus

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5
Q

One of the cardinal signs of acute inflammation (5)

A

rubor

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6
Q

Normally non-sterile site of the human body (11)

A

Conjunctiva

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7
Q

Secondary lymphoid organ (5)

A

Spleen

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8
Q

A localised collection of pus surrounded and walled off by a collection of capillaries, neutrophils
and fibroblasts (7)

A

Abscess

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9
Q

Fluid that filters from the circulatory system and has a high protein concentration and contains
cellular debris (7)

A

Exudate

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10
Q

Genetic material of retroviruses (3)

A

RNA

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11
Q

The _____ receptor molecule is required to enable HIV to bind to cells (3)

A

CD4

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12
Q

Term used to describe a rod-shaped bacterium (8)

A

Bacillus

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13
Q

Cell type predominantly associated with acute inflammation (10)

A

neutrophil

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14
Q

The most common cause of leg ulcers (6)

A

Venous

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15
Q

Thymic aplasia leading to lack of T-cells is known as ____ syndrome (8)

A

DiGeorge

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16
Q

Tuberculosis and sarcoidosis are examples of _____ disease (13)

A

granulomatous

17
Q

Pseudomembranous colitis is caused by (11,9)

A

Clostridium difficile

18
Q

End stage of liver disease (9)

A

cirrhosis

19
Q

Class of signalling molecule secreted by activated macrophages (9)

A

cytokines

20
Q

In a healthy individual, an area of the body in where you would likely detect colonisation with
Staphylococcus aureus? (4)

A

nose

21
Q

Term used to describe the adhesion of neutrophils to the vascular endothelium at sites of acute
inflammation (11)

A

Pavementing

22
Q

An example of a Type III hypersensitivity disease occurring through an intravenous route (9)

A

Arthritis

23
Q

Autoimmune disease associated with “butterfly rash” (3)

A

SLE

24
Q

Process by which neutrophil polymorphs are attracted towards certain chemicals in solution (10)

A

Chemotaxis

25
Q

A common component of the cell wall of most fungi (6)

A

Chitin