Lecture 2: Role of Pathology in medicine Flashcards

1
Q

What is Pathology?

A

The scientific study of disease.

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2
Q

Define disease.

A

“an abnormality of the body that causes loss of normal health”

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3
Q

What percentage of patient diagnosis’ are involved with clinical Labatory medicine?

A

70%

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4
Q

What areas are involved in clinical Labatory medicine?

A

Immunology
Microbiology
Haematology
Chemical Pathology
Cellular Pathology
Genetics Cytogenetics

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5
Q

What is taken in consideration during scientific study of disease?

A

Epidemiology
Aetiology
Anatomical changes
Biochemical changes
Functional changes
Natural history
Prognosis

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6
Q

What are the limited responses that cells and tissues have to disease? (Basic pathological Responses)

A

Adaption of cells to their environment
What happens when cells cannot adapt
Abnormal cell growth eg Cancer
Tissue responses to injury
Healing
Genetic factors
Immune factors
Environmental factors

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7
Q

When do we investigate how the same pathology behaves differently in different systems? (Systematic Pathology)

A

Specific Diseases
Individual organs or body systems

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8
Q

What is the process in pathology?

A
  1. Epidemiology
  2. Aetiology
  3. Pathogenesis
  4. Pathological and clinical features
  5. Prognosis
  6. Treatment
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9
Q

What do we consider when classifying tumours

A

Structure of origin
Benign vs. malignantq

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10
Q

Prefix Ana- meaning?

A

Absence (Anaplasia)

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11
Q

Prefix Dys- meaning?

A

Disordered (Dysplasia)

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12
Q

Prefix Hyper- meaning?

A

Excess over normal (Hyperthyroidism)

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13
Q

Prefix Hypo- meaning?

A

Deficency below normal (Hypothyroidism)

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14
Q

Prefix Meta- meaning?

A

Changes from one state to another (Metaplasia)

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15
Q

Suffix -itis meaning?

A

Inflammatory process (Appendicitis)

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16
Q

Suffix -oma meaning?

A

Tumour (Caricinoma)

17
Q

Suffix -osis meaning?

A

State or condition (Osteoarthrosis)

18
Q

Suffix -oid meaning?

A

Bearing a resemblance to (Rheumatoid disease)

19
Q

Suffix -penia meaning?

A

Lack of (Thrombocytopenia)

20
Q

Suffix -cytosis meaning?

A

Increased number of cells (Leukocytosis)

21
Q

Suffix -ectasis meaning?

A

Dilation (Bronchiectasis)

22
Q

Suffix -plasia meaning?

A

Disorder of growth (Hyperplasia)

23
Q

suffix -opathy meaning?

A

Abnormal state lacking specific characteristics (Lymphadenopathy)

24
Q

What does Molecular pathology include?

A

FISH
DNA sequencing
Whole genome sequencing
RNA sequencing

25
Q

What does digital pathology include?

A

Fusion of computing and histopathology
Instant access to unlimited database and archives
Image recognition and processing
3D

26
Q

What does three dimensional pathology?

A

Digital scanning
Assembly
Virtual 3D histology
3D modeling