The Visual System Flashcards
Pathway for light
Light-> to posterior chamber-> through all layers of the retina by the bipolar cells included-> back to layer 2 of the retina by ganglionic cells-> brain LGN of thalamus-> primary visual cortex and the calcarine sulcus
Three layers of the eye
Fibrous Layer: external layer, SCLERA and CORNEA
Vascular Layer: CHOROID, CILIARY BODY, IRIS
Retina: inner sensory layer, OPTIC NERVE
Fibrous Layer: Sclera and cornea
- Sclera: fibrous external layer- protection and extraocular muscles insertion anteriorly
type 1 collagen, Dense Regular CT, some vasculature - Cornea: transparent and avascular (can be injured and fixed)
a. Corneal epithelium- nonkaratinized strat. squamous
b. Anterior limiting membrane (Bowman Membrane)- BM of the corneal epithelium
c. Thick Stroma - keratocytes
d. Posterior limiting membrane (Descemet’s Membrane)- BM for the endothelium layer
e. Inner endothelium
The Limbus
Transition from the cornea to the sclera.
This is the end of the bowman membrane
This is the start of the conjunctiva (anterior sclera and lines eyelids)
Has stem cells that move to the corneal epithelium
Vascular Layer (uvea): choroid
- Choroid: loose CT, high vascularized, many MELANOCYTES, where light that is not reflected off the retina goes
dark layer- prevent light from entering eye except through pupil
bruch membrane- Basal lamina for retina pigment layer (anterior boundary for the choroid)
Vascular Layer (uvea): ciliary body
- Ciliary Body: shape of LENS, ciliary muscels, processes, zona
Vascular Layer (uvea): Iris
- Iris: makes the pupil in the middle, outer boundary of the lens
Retina: makes the optic cup
- Outer Pigment Epithelium layer- simple cuboidal (surrounds the neuronal layer)
- Inner Neural Layer- think strat. with many neurons and photoreceptors (10 LAYERS)
optic disk
blind spot
fovea
highest acuity vision, highest amount of cones
Peripheral retina including the ora serrata
high rods
Pigmented Epithelium layer
surrounds the neural layer
- absorbs scattered light: helping choroid
- Isomerize all-trans -> 11- cis and takes it back to the photoreceptors
- Phagocytosis of waste form photoreceptors
- Remove free radicals and secretes ATP
- immunomodulatory factors
Neuronal Retina 10 layers
LIGHT–>through all layer to the bottom layer
- Pigmented Layer
- Rods and Cones outer segments
- Outer Limiting Layer: hold photoreceptors to müller cells
- Outer Nuclear Layer- rods and cones cell bodies
- Outer Plexiform Layer: fiber/axons of R/C–> Bipolar Cells
- Inner Nuclear Layer: Bipolar Cells
- Inner Plexiform Layer: fiber/axons of Bipolar cells –> Ganglionic Cells
- Ganglionic Layer: Ganglionic cell bodies (thicker in the center of the retina)
- Nerve Fibre Layer: Ganglionic axons that go to OPTIC DISC and converge to form CN1
- Inner Limiting Membrane: BM covered by Müller cell processes
Rods Inner Segment
Inner Segment= glycogen, mitochondria, polyribosomes, to make proteins for cells
Rods Outer Segments
Outer Segment= primary cilium, photosensitive, has flattened membranous discs
Rods Outer Segments - DISCS
Has rhodopsin
continuously shed and replaced
old disc= pushed superficially to be shed and digested by PE
Cones
color vision if there is adequate bright light
has 3 types of IODOPSIN
Red, Green, Blue
discs are shed not as often
Specialized area of the Retina - FOVEA CENTRALIS
highest cones, 20/20 acuity, in the center of the retina
as you move peripherally the acuity becomes more 20/600
HAS NO BVS, Cell bodies/Axons of the Ganglionic and Inner Nuclear Layer (bipolar cells)
Specialized area of the Retina - MACULA LUTEA
surrounds fovea for protection of cones
uv filter and antioxidant
Specialized area of the Retina - Optic Disc
Head of the optic Nerve,
only ganglionic axons, BLIND SPOT