The T Lymphocyte Response Flashcards
Lymphocytes are another type of
white blood cell
Lymphocytes are another type of white blood cell
They play an important part in the
specific immune response
Cell mediated response
They are smaller than phagocytes
They have a …………….. that fills most of the cell
nucleus
lymphocytes are produced in
Bone marrow at birth
There are two types of lymphocytes (with different modes of action). The two types of lymphocytes are:
T-lymphocytes (T cells)
B-lymphocytes (B cells)
T-lymphocytes and the cellular immune response
Immature T-lymphocytes leave the bone marrow to mature in the ………
thymus
Mature T-lymphocytes have specific cell surface receptors called
T cell receptors
Mature T-lymphocytes have specific cell surface receptors called T cell receptors
These receptors have a similar structure to …………….
and are specific to…….
antibodies and are each specific to one antigen
In bone marrow immature T lymphocytes divides by mitosis
In the thymus they develop……….
T cell receptors in cell surface membrane
Mature T lymphocytes have different
T cell receptors
T-lymphocytes are activated when they encounter and bind to
their specific antigen that is being presented by one of the host’s cells (host cells being the human’s own cells)
This antigen-presenting host cell might be a macrophage or a body cell that has been invaded by a
pathogen and is displaying the antigen on its cell surface membrane
These activated T-lymphocytes (those that have receptors specific to the antigen) divide by
mitosis to increase in number (similar to the clonal selection and clonal expansion of B-lymphocytes)
These T-lymphocytes differentiate into two main types of T cell
helper T cells
cytotoxic T cells(also known as killer T cells
