replication of hiv Flashcards

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1
Q

step 1 When the virus enters the bloodstream it infects a certain type of lymphocyte -

A

helper T cells

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2
Q

Normally lymphocytes seek out and destroy pathogens that enter the body, producing antibodies that attach to pathogens and enhancing phagocytic activity

HIV avoids being recognised and destroyed by lymphocytes by

A

repeatedly changing its protein coat

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3
Q

second stage

The virus uses the cell machinery of helper T-cells to multiply how

A

Viral RNA enters the cell

Viral reverse transcriptase enzymes produce a DNA copy of the viral RNA

The DNA copy is inserted into the chromosomes of the cell

Each time the cell divides it copies the viral DNA

The infected cells remain normal as the viral DNA is inactive

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4
Q

third stage

At this stage, the individual is HIV positive and will have antibodies against the virus

After a period of time (possibly years) the viral DNA within the host cells becomes active and

A

It takes control of the helper T cell

More HIV particles are produced

This causes the helper T cell to die

As a result, thousands of new HIV particles are released which are able to infect other helper T cells

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5
Q

forth stage Gradually the virus reduces the number of helper T cells in the immune system
till

A

B cells are no longer activated

No antibodies are produced

This decreases the body’s ability to fight off infections, eventually
leading to AIDS (Acquired immune deficiency syndrome)

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