Antigens Flashcards
Antigens
Every cell in the human body has markers that identify it
Microorganisms (both pathogenic and non-pathogenic), such as bacteria and viruses, also have their own unique markers
These markers are called and what do they allow
antigens (which are macromolecules) and they allow cell-to-cell recognition
Antigens are found on
cell surface membranes, bacterial cell walls, or the surfaces of viruses
Some glycolipids and glycoproteins on the outer surface of cell surface membranes act as antigens
Antigens can be either
self antigens or non-self antigens
Antigens produced by the organism’s own body cells (those that the immune system does not recognise as foreign antigens) are known as
self antigens
Self antigens do not stimulate an immune response
Antigens not produced by the organism’s own body cells (those that the immune system recognises as being foreign eg. the antigens found on pathogenic bacteria and viruses or if a person receives a different blood type during a transfusion) are known as
non-self antigens
Non-self antigens stimulate an immune response
Antigen Variability
Some pathogens exhibit antigen variability
The antigens present on their surface …………
change frequently due to genetic mutations
The antigens present on their surface change frequently due to genetic mutations
This poses a problem for the immune system of many mammal hosts as lymphocytes and memory cells produce a
specific immune response
The surface receptors on lymphocytes and memory cells are complementary in shape to
only one antigen
When the antigen on a pathogen changes the lymphocytes and memory cells can
no longer attach
As a result of antigen variability As a result, there is no ………..
The host gets…………………..
As a result, there is no secondary immune response
The host gets infected and suffers from the disease again
The cold virus and flu virus are common pathogens that exhibit antigen variability
Individuals can catch the cold and flu year after year as the antigens on the viruses change and are not recognised by their immune system
The different types of pathogen include
viruses, bacteria, fungi and protozoans(protists!