the skin 2 Flashcards

1
Q

Where do langerhans cells originate from?

A

bone marrow

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2
Q

Describe langerhans cells

A
  • dendritic
  • antigen presenting cells that survey microbiome of skin
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3
Q

Where are meissner corpuscles located?

A

dermal papillae

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4
Q

What is a basal cell carcinoma?

A
  • borderine malignant tumour
  • hair follicle origin
  • related to sun exposure
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5
Q

What do merkel cells do?

A

mediate tactile sensation/light touch

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6
Q

What does the Pacinian corpuscle detect?

A

vibrations

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7
Q

How can you recognise the Parcinian corpuscle on an image?

A

it’s got spirals kind of

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8
Q

What is the basement membrane made of?

A

collagen type 4

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9
Q

Which functions does the basement membrane have?

A
  • resistance to shearing forces
  • ties together dermis and epidermis
  • control of epithelial-mesenchymal interactions
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10
Q

What is the dermis made of?

A
  • dense connective tissue
  • collagen, elastin
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11
Q

What epidermal appendages does the dermis contain?

A
  • pilosebaceous units
  • sweat glands
  • apocrine glands
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12
Q

What makes up the pilosebaceous unit?

A
  • hair
  • sebaceous glands
  • smooth muscle/arrector pili muscles
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13
Q

What 2 types of sweat glands are there?

A
  • eccrine
  • apocrine
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14
Q

What is the most common skin tumour?

A

basal cell carcinoma

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15
Q

What do eccrine sweat glands produce?

A

watery sweat

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16
Q

What do apocrine sweat glands produce?

A

much thicker, oily secretions, and hormones

17
Q

How does vasodilation cool us down?

A
  • increased blood flow into dermis
  • so more heat into dermis
  • so more loss of heat
18
Q

Where are apocrine sweat glands found?

A
  • axilla
  • groin
  • external ear canal
  • eyelids
  • nipple
19
Q

What are the apical snouts?

A
  • iece of cell that comes off as part of secretory process of apocrine glands