the skin 2 Flashcards
Where do langerhans cells originate from?
bone marrow
Describe langerhans cells
- dendritic
- antigen presenting cells that survey microbiome of skin
Where are meissner corpuscles located?
dermal papillae
What is a basal cell carcinoma?
- borderine malignant tumour
- hair follicle origin
- related to sun exposure
What do merkel cells do?
mediate tactile sensation/light touch
What does the Pacinian corpuscle detect?
vibrations
How can you recognise the Parcinian corpuscle on an image?
it’s got spirals kind of
What is the basement membrane made of?
collagen type 4
Which functions does the basement membrane have?
- resistance to shearing forces
- ties together dermis and epidermis
- control of epithelial-mesenchymal interactions
What is the dermis made of?
- dense connective tissue
- collagen, elastin
What epidermal appendages does the dermis contain?
- pilosebaceous units
- sweat glands
- apocrine glands
What makes up the pilosebaceous unit?
- hair
- sebaceous glands
- smooth muscle/arrector pili muscles
What 2 types of sweat glands are there?
- eccrine
- apocrine
What is the most common skin tumour?
basal cell carcinoma
What do eccrine sweat glands produce?
watery sweat