The Motor System Flashcards
Where are the cell bodies of the upper motor neurones found?
In the primary motor cortex
Where are the cell bodies of the lower motor neurones found?
In the ventral horn of the spinal cord and brain stem
What are the basic units of the motor system (descending tracts)?
Upper motor neurones project onto lower motor neurones which project onto muscles
Where will you not find upper motor neurones (within the CNS)?
In the cerebellum or the basal ganglia
Where are upper motor neurones vulnerable to damage?
Vulnerable within the CNS only
What is the main motor tract of interest?
Lateral Corticospinal Tract
What do upwards extensions of the vertebral horns create?
Create cranial nerve motor nuclei
Explain the principles of the patellar reflex arc
- Activation of receptors in the quadracepts travels to spinal cord via the dorsal root ganglion
- Sensory neurones synapse onto Motor neurones in the ventral horn at L3 to activate contraction of the quads
- At the same time… the sensory neurones project down to L5 to activate an inhibitory inter neurone that switches off the hamstrings
- Causes knee jerk reflex
What are the cardinal signs of lower motor neurone damage?
- Hypotonia (little muscle tone)
- Areflexia (loss of relex arc)
- Atrophy (of the myotomes supplied)
- Weakness (if only 1 segment involved- most muscles recieve input from 2 spinal nerves)
- Fasciculation (flickering contractions under the skin)
- Fibrillation (uncoordinated contraction of individual muscle fibres)
Why does damage to lower motor neurones cause atrophy?
Lower motor neurones supply action potentials and growth factors (trophic factors)
These growth factors are lost if the neurone is transected → atrophy
What type of input are the majority of projections onto lower motor neurones?
The majority of inputs to LMN are from inhibitory interneurones
What is the name given the the tracts in which UMN from the face and neck terminate in the brainstem?
Corticonuclear / Corticobulbar
Describe the route of neurones in the motor pathway
- Primary motor neurones begin in the primary motor centre of the cortex
- Multiple motor fibres descend as the corona radiata
- Motor fibres then converge into the internal capsule (dense white matter)
- Upper motor neurones continue to descend in the cerebral peduncle of the midbrain and then through the anterior/ventral pons
- At the level of the medullary pyramids upper motor neurones can take 2 paths
- 85% decussate and form the lateral corticospinal tract
- 15% descend ipsilaterally as the anterior/ ventral corticospinal tracts and the decussate at the level of the lower motor neurone of interest
Explain the organisation of upper motor neurones supplying the muscles of the face
- Muscles of facial expression are supplied by the facial nerve (CN VII)
- The facial nerve motor nuclei is split into an upper and lower half
- superior 1/2 supplies upper facial musculature
- inferior 1/2 supplies inferior facial musculature
- The UMN supplying the superior 1/2 of the face supplies the superior motor nuclei contralateral AND ipsilateral
- The UMN supplying the inferior 1/2 of the face supplies the inferior motor nuclei contralaterally only
Explain why a stroke is forehead sparing in relation to facial muscle weakness
The upper half to the face i.e. forehead, recieves input from both the left and right side due to the contralateral and ipsilateral supply of upper motor neurones to the upper facial nerve nuclei
Therefore damage to one side of the brain in stroke will lose input to the lower half of the face but the upper half is supplied by the unaffected side