The heart and mediastinum Flashcards
Describe pulmonary circulation
Low resistance
pressure 20/10mmHg
Describe the systemic circulation
High variable resistance
120/80mmHg
What are the 3 layers of the heart wall?
3 layers of the heart wall
Epicardium (also visceral/serous pericardium)
Muscular myocardium
Endocardium (monolayer endothelial cells)
What’s the function of pericardial cavity?
Heart sits in it and allows friction free contraction within chest
Two layers of pericardium?
Outer fibrous layer (continuous with central tendon of diaphragm)
Serous layer inside
What is the pericardial sac?
Double layered sac, sealed to diaphragm which surrounds heart apart from where great vessels enter/leave
What are some abnormalities that arise of the pericardium?
Pericarditis: inflammation of pericardium, people complain with chest pain due to friction (heart beats and it rubs)
Tamponade: effusion of pericardium (e.g. post viral infection or shot in heart ), fluid builds up between 2 pericardial layers and insults pumping action of the heart
What is meant by pericardial sinus?
Cavities produced by pericardium around the heart
Two types of pericardial sinuses?
Oblique sinus between heart and great vessels
Transverse sinus: around aorta and pulmonary trunk posterior to heart
How is transverse sinus formed?
Dorsal mesocardium breaks down
Describe orientation of heart in thorax
Lies obliquely, RV and RA face anteriorly, LV and LA posterior
Describe the surface borders of the heart
Superior border: line following 2nd left costal cartilage to 3rd right costal cartilage
Right border: 3-6 right intercostal cartilage
Apex (left border): in 5th intercostal space in mid clavicular line
What happens in situs inversus
Mirror image positioning of all organs (compatible with life)
What is situs solitus?
Normal
What is fibrous skeleton formed of?
Cartilaginous ring at level of membranous ventricular septum (connective tissue frame which functions to electrically isolate the atria from the ventricles)
What is the function of fibrous skeleton of heart?
Non conducting separation of atria and ventricles, electroinsulation so impulses must pass through AVN
Support for valves
What are the principal venous structures draining to heart?
SVC, IVC (drain into right atrium)
Pulmonary veins
Coronary sinus
What is the coronary sinus?
A collection of veins joined together to form a large vessel (coronary sinus) that empties blood into right atrium
Where does coronary sinus run and which veins does it receive?
Runs in AV groove
Receives, great, middle and small cardiac vein
What is the name of the right AV valve?
Tricuspid valve
What does fibrous skeleton contain?
AV, aortic and pulmonary valve orifices
What are 3 cusps of tricuspid valve attached to?
Fibrous ring surrounding AV orifice
Structure of pulmonary/aortic valves?
3 semi lunar cusps
What veins does the left atrium receive?
4 pulmonary veins (2 inferior, 2 superior 2)
Why does left atrium have smooth walled interior?
Formed by incorporation of primitive pulmonary veins in development
What is the left AV valve?
Mitral valve
Describe structure of mitral valve?
2 cusps and papillary muscles larger than counterparts on right side
What are aortic sinuses?
Formed behind cusp of each valve as a bulge in aortic wall
What do left, right posterior and anterior aortic sinuses supply?
Left Posterior - origin of left coronary artery
Right anterior: origin of right coronary artery
Right posterior: no artery
What happens to blood supply to ventricular wall in systole, why, therefore, when does most coronary perfusion occur?
High pressure generated shuts off coronary circulation
Most coronary perfusion in diastole
How does heart blood supply show end organ circulation?
Branches of coronary artery are functional end structures (anastomoses between LCA and RCA rare and inefficient) and sensitive to obstruction
In terms of coronary arteries, why can myocardial infarctions/angina be caused?
Occlusion of major coronary arteries and inefficienct anastomoses between RCAs and LCAs
Where does coronary circulation originate from?
RCA and LCA arise above aortic valve at left/right aortic sinuses
Which layers of heart do coronary arteries supply?
Myocardium and epicardium
What do LCA and RCA supply generally?
LCA: left ventricles, atria and IV septum
RCA: right ventricles, atira and septum