GI tract and abdominal viscera Flashcards
What is the division of the foregut and midgut is distinguished by?
The ampulla of Vater (common bile and pancreatic duct)
duodenal papilla
What controls secretions from the ampulla of vater?
Sphincter of Oddi
What spinal levels does the foregut receive sympathetic innervation from and receive visceral afferents from?
T5-T9 levels
What sympathetic nerve principally supplies the foregut, what organs does it innervate?
Greater splanchnic nerve to coeliac ganglia
Postganglionic innervates liver, spleen, stomach and duodenum
What is the division between the midgut and hindgut?
Approximately 2/3 along the transverse colon
What spinal levels does the midgut receive sympathetic innervation from and receive visceral afferents from?
T10-T11 levels
What sympathetic nerve principally supplies the midgut, what organs does it innervate?
Lesser splanchnic nerve to the superior mesenteric ganglia
Postganglionic innervates part of the small intestine, ascending colon and part of the transverse colon.
What spinal levels does the hindgut receive sympathetic innervation from and receive visceral afferents from?
L1 level
What sympathetic nerve principally supplies the hindgut, what organs does it innervate?
Lumbar splanchnic nerves to inferior mesenteric ganglion
Postganglionic innervates the descending colon, sigmoid colon and rectum.
What is the principle blood supply to foregut, midgut and hindgut?
Foregut - coeliac artery
Midgut - superior mesenteric artery
Hindgut - inferior mesenteric artery
What is the parasympathetic innervation of the GI tract?
Vagus (X) up to the transverse colon
Then pelvic splanchnic nerves (S2-S4)
What makes up the abdominopelvic cavity?
Abdomen proper
Pelvic cavity
What is the peritoneum?
Serous membrane which lines the walls of the abdominopelvic cavity and covers the abdominopelvic organs.
What are the two layers of the peritoneum?
Inner visceral and outer parietal
What is the histological appearance of the peritoneum?
Layer of squamous mesothelium supported by a thin layer of connective tissue
What is the space between the visceral and parietal perineum known as and what is in there?
Peritoneal cavity and within the cavity is a small amount of peritoneal fluid.
What two parts divides the peritoneal cavity?
Greater and lesser sac
What is the opening between the greater and lesser sac called?
Epiglotic foramen
What gives the blood and nerve supply of the visceral peritoneum and why?
Becomes attached to, and part of, the structure of the organ itself.
The blood supply, lymphatic drainage and nerve supply of the visceral peritoneum are the same as those of organ it covers.
What gives the blood and nerve supply of the parietal peritoneum?
Blood supply, lymphatic drainage and nerve supply of parietal peritoneum are the same as those of the associated abdominopelvic wall.
Define intraperitoneal and retroperitoneal
Intraperitoneal: organ lies within the peritoneal space, suspended by mesentery
Retroperitoneal: organs lie in the retroperitoneal space behind (retro) the peritoneum - in contact with the posterior abdominal wall.
What does it mean to be secondarily retroperitoneal?
Organs that were once suspended within the abdominal cavity by mesentery but migrated posterior to the peritoneum during the course of embryogenesis to become retroperitoneal.
What is mesentery?
Where the organ is some distance from the posterior abdominal wall
The peritoneum is drawn into a double layer, a mesentery.
What occupies the space between the two peritoneal layers of a mesentery, why is this good?
Fat, blood vessels, lymphatics and nerves
Can reach the gastrointestinal tract without piercing the peritoneum.
Which structures are retroperitoneal?
Suprarenal (adrenal) Aorta + IVC Duodenum (2nd and 3rd) Pancreas (not tail) Ureter Colon (descending and ascending) Kidney Esophagus Rectum
Which organs are intraperitoneal?
Ileum, jejunum, transverse and sigmoid colon, liver and stomach, spleen, tail of pancreas
Describe nature and length of the oesophagus
25cm fibromuscular tube
What does oesophagus do?
Transports food form pharynx to stomach
Describe what oesophagus spans
Inferior border cricoid cartilage (c6), cardiac orifice of stomatch T11
Describe position of oesophagus in mediastinum
Posterior mediastinum
Passes through the diaphragm at T10
Describe what makes up the upper oesophageal sphincter and what it does
Cricopharyngeus muscle
prevents air entering oesophagus
What is the junction between the stomach and oesophagus called?
Gastro-oesophageal junction
Where is the gastrooesophageal junction situated?
Left of T11 vertebra
What 5 features make up the lower oesophageal sphincter?
Oesophagus enters stomach at acute angle
Walls of intra-abdominal section of oesophagus can be compressed (when increase in intrabdominal pressure)
Folds of muscularis mucosa occlude lumen
Valve formed by circular muscle fibres at lower abdomen
Oesophagus narrows as it passes through right crus
Which part of diaphragm does oesophagus pass through?
Right crus
What is the purpose of lower oesophageal sphincter?
Prevent reflex of acidic gastric contents into oesophagus
What are 4 natural narrowings of oesophagus?
Cricopharyngeal sphincter
Where aortic arch crosses it
Where left main bronchus indents it
Diaphragmtic hiatus
What runs either side of cervical oesophagus?
Common carotid arteries
Recurrent laryngeal nerves
What supplies cervical oesophagus?
Inferior thyroid artery
What drains cervical oesophagus?
Vertebral, brachiocephalic, inferior thyroid veins
What provides lymphatic drainage to cervical oesophagus?
Deep cervical nodes
What innervates cervical oesophagus?
Recurrent largneal and middle cerivcal ganglion (symp)
What 4 things is thoracic oesophagus anterior of?
T vertebrae
thoracic duct
azygous vein
descending aorta
What supplies thoracic oesophagus with blood?
Oeosphageal branches from aorta and bronchial arteries
What provides venous drainage to thoracic oesophagus?
Azygous and hemiazgous vein
What provides lymph drainage to thoracic oesophagus?
Tracheaobronchial and posteiror mediastinal nodes
What innervates thoracic oesophagus?
Vagus, greater splachnic nerve (symp)
What changes histologically at gastrooeosphageal junction?
Change from oesophageal to gastric mucosa
Is the abdominal oesophagus retroperitoneal or intraperitoneal?
Retroperitoneal
Anterior surface covered with parietal peritoneum and abdominal oesophagus lies outside (behind) peritoneal cavity
Which arteries supply abdominal oesophagus?
Branches of left inferior phrenic and left gastric arteries
What drains abdominal oesophagus?
Left gastric vein (drains into portal system) Azgous vein (drains into systemic)
What provides lymphatic drainage for abdominal oesophagus?
Left gastric and coeliac nodes
What innervates abdominal oesophagus?
Vagus
Which region of abdomen does stomach lie?
Left hypochondrium (superoir aspet of abdomen)
What does stomach do?
Break up food and mixes with secretions (e.g. pepsin, HCl, intrinsic fator)
What does stomach present to duodenum?
Chyme
What are the five regions of the stomach
Cardia Fundus Body Antrum Pylorus
What is fundus normally filled by?
Gas
What is fundus seen as on x-ray?
Gastric bubble
Which part of pylorus is widest?
Pyloric antrum
Where is pyloric sphincter, what does it do?
Junction with duodenum, regulates flow of stomach contents
What is pylorus crossed vertically by?
Crossed vertically by constant vein of mayo
When does stomach empty?
When intragastric pressure overcomes resistance of pylorus (controlled by nerves/hormones reflexes)
What happens in pyloric stenosis?
Narrowing of pyloric passage e.g. due to muscle hypertrophy. Leads to projectile vomiting, malnourishment
What does angular notch indicate?
Junction of body and pyloric region of stomach
What are omenta formed of?
Peritoneum folded over itself (i.e. 2 layers of peritoneum)
Where do gastric ulcers mainly occur?
Lesser curvature
What does greater omentum attach to?
Hangs from greater curvature and attaches to transverse colon
What does lesser omentum attach to?
Arises at lesser curvature and ascend to attach to liver
What is anterior to stomach?
Diaphragm and left lobe of liver
What is posterior to stomach?
Left kidney, spleen, aorta, coeliac trunk ,transverse mesocolon
What does greater omentum contain that helps with immunity?
Lymph nodes
Where does the greater omenta hang, what name is it given for this?
Lies superficial to the small intestine in the abdomen - fatty apron-like fold
What ligaments are subdivided from greater omentum?
Gastrosplenic omentum: stomach to the spleen,
Gastrophrenic ligament: stomach to underside of left dome of the diaphragm
Gastrocolic ligament: stomach to the transverse colon
Splenorenal ligament: the left kidney to the spleen (occasionally considered part of the greater omentum)
Phrenicosplenic ligament: thoracic diaphragm to spleen
What does the splenorenal ligament contain?
The splenic artery and vein
The tail of the pancreas, the only intraperitoneal portion of the pancreas.
What ligaments are subdivided from the lesser omentum?
Hepatogastric ligament: lesser curvature of the stomach to the liver.
Hepatoduodenal ligament: liver to the duodenum
What does the hepatoduodenal ligament contain?
Common bile duct, hepatic artery (proper) and hepatic portal vein
Describe blood supply to lesser curvature
Left and right gastric arteries anasotmose and run in lesser omentum
Describe blood supply to upper part of greater curvature?
Short gastric arteries + left gastroepiploic artery (both run in gastrosplenic ligmaent)
Describe blood supply to lower part of greater curvature
Right gastroepiploic runs in greater omentum
Describe venous drainage of the stomach?
Left and right gastric veins (lesser curvature) drain to portal vein direct
Left gastroepiploic and short gastric veins (upper greater curvature) drain into splenic veins
Right gastroepiploic vein (lower greater curvature) drains into superior mesenteric vein
(Splenic and superior mesenteric vein merge forming portal vein)
Describe lymph from stomach regions that drains into coeliac nodes.
Lesser curvature: left and right gastric nodes
Upper left side of greater curvature: splenic and pancreatic nodes
Lower greater curvature: gastroepiploic and pyloric nodes
Describe innervation to stomach
Symp fibres: coeliac plexus (T6-T9), nerves pass here via greater splachnic nerve
Para: vagus from anterior and posterior vagal trunks
Describe what anterior vagal trunk supply
Gastric branches, large hepatic branches and branches to pylorus
What does posterior trunk of vagus plexus supply?
Posterior stomach, large coeliac branch forms coeliac plexus.
Describe where small intestine extends to and from
Pylorus to ilecocaecal junction
What are 3 parts of small intestine?
Duodenum, jejunum, ileum
Four parts of duodenum
Superior, descending, inferior, ascending
What does duodenum wrap around?
Head of pancreas
Is duodenum retroperitoneal or intraperitoneal?
Retroperitoneal
What does duodenum receive?
Chyme from stomach, bile from gall bladder, pancreatic juices from pancreas
Level of superior duodenum?
L1
What small intestine site is most common for ulceration?
Superior duodenum (H Pylori)
What is posterior to superior duodenum?
Portal vein, common bile duct, IVC
What is anterior to superior duodenum?
Liver and gall bladder
What level is descending duodenum?
L1-L3
What does descending duodenum lie posterior to?
Transverse colon
What does descending duodenum lie anterior to?
Right kidney
What is major duodenal papilla?
Opening at which pancreatic secretions and bile secretions enter from ampulla of Vater
Where does accessory pancreatic duct enter duodenum?
Minor papilla above major one
What level is inferior duodenum?
L3
What does inferior duodenum cross over?
IVC and aorta
Level of ascending duodenum?
L2-L3