Spine Flashcards
How many cervical vertebrae does the spine consist of?
7
How many thoracic vertebrae does the spine consist of?
12
How many lumbar vertebrae does the spine consist of?
5
How many sacral vertebrae does the spine consist of, are they discrete?
5, fused vertebrae
How many coccygeal vertebrae does the spine consist of?
3-5
What lies inbetween adjacent vertebrae?
Intervertebral discs
What occupies the vertebral canal from C1 to L1
Spinal cord
What occupies the vertebral canal from L1 down?
Corda equina
What does the spinal cord give rise to?
Nerve roots
Where do nerve roots emerge relative to the spinal cord?
Via the intervertebral foramen, below the pedicle of each vertebrae
How many nerve roots are there in the cervical region?
8
Why is there 8 nerve roots but only 7 vertebrae in the cervical region?
Root 1 emerges above C1.
What do nerve roots exit the spinal cord through?
Intervertebral foramen
Describe the curvature of the spine?
Cervical Lordosis
Thoracic Kyphosis
Lumbar Lordosis
What is a lordosis and a kyphosis?
Lordosis - posterior concavity
Kyphosis - posterior convexity
What can cause lateral scoliosis?
Ventral and medial somite cells surrounding the notochord and neural tube fail to migrate (to meet in the middle), on one side
What are the primary spinal curvatures? When do they develop?
Thoracic kyphosis and sacral curvature
During foetal development
What are the secondary spinal curvatures? When do they develop?
Cervical and lumbar lordosis
After birth
What forms first, lumbar or cervical lordosis?
Cervical
What signals somites to differentiate into sclerotome and dermomyotome?
Shh induces the most medial of somite cells to form sclerotome
What releases Shh that patterns the spine?
Notochord
What does the sclerotome form?
Vertebrae
Where does the sclerotome lie relative to the myotome?
Medial (towards notochord)
When sclerotome cells move medially what happens to it?
Cells meet the other sclerotome cells from the other side to form the vertebral body
How does sclerotome on fuse in a craniocaudal axis to form vertebrae?
The lower half of one sclerotome (from one somite) fuses with the upper half of the adjacent one to form each vertebral body.
Where do the spinal nerves emerge through a sclerotome?
Through fissure in one NOT through adjacent ones
What genes determine appropriate shapes of vertebrae along the spine?
Hox
What type of bone is a vertebrae?
Irregular bone
What type of ossification do vertebrae undergo?
Endochonral ossification
Describe the basic configuration of a vertebra
Vertebral body
Posterior part of a vertebra joins the vertebral body via two pedicles
Vertebral foramen created by body, pedicles and posterior
Laminae join together the central spinous process with the transverse processes.
What joins up the spinous and transverse processes?
Laminae
What joins the body with the posterior vertebrae?
Pedicles
What forms the intervertebral foramen (bone)?
Above and below the pedicles are vertebral notches (superior and inferior).
When the vertebrae articulate the notches align with those on adjacent vertebrae and these form the openings of the intervertebral foramina.
Which articular process is lined with hyaline cartilage?
Superior
What is characteristic about the body of cervical vertebrae?
Small
What is characteristic about the vertebral foramen of cervical vertebrae?
Large
What foramen is unique to cervical vertebra?
Transverse (vertebroarterial)
Where are transverse foramina (cervical spine)?
Lateral to body