The Guide Ch1 Flashcards
True or False: Replacement refers to methods that avoid using animals
in research.
True
Replacement may be achieved by
a. Using inanimate study systems such as computer models
b. Using animals that are lower on the phylogenetic tree
c. Both a and b
c
Modification of animal husbandry to experimental procedure to
minimize pain/stress/suffering is known as
a. replacement
b. reduction
c. refinement
c
True or False: The Guide establishes the minimal care, ethical and
practice standards for the use of vertebrate animals in biomedical
research.
True
Obtaining comparable information from fewer animals or maximizing information obtained from a given number of animals without increasing pain or distress may be achieved by:
a. Using newer technologies
b. Analysis of experimental design
c. Use of appropriate statistical method
d. Control of environmentally related variability in animal housing and study areas
e. All of the above
e. All of the above
The animal care and use program includes:
a. Establishment and support of an IACUUC
b. Facilities in which animals will be housed and studied
c. Policies, procedures, standards and practices established to ensure humane animal care
d. Staffing
e. Organizational structure
f. All of the above
f. All of the above
In the United States of America, the use of animals for research is governed by:
a. The Animal welfare act
b. PHS policy
c. The GUIDE
d. All of the above
d. All of the above
The Guide covers:
a. traditional laboratory animals
b. agricultural animals
c. wildlife
d. aquatic species
e. all of the above
e. all of the above –> ANY VERTEBRATE ANIMAL
True or False: The guide governs animals produced for and used in
research, testing, teaching.
True
True or False: Replacement refers to methods that avoid using animals in research.
True
Replacement may be achieved by which of the following?
a. Using inanimate study systems such as computer models
b. Using animals that are lower on the phylogenetic tree
both are correct
True or False: The Guide is written in general terms so that its recommendations may be applied in diverse institutions and settings.
True
True or False: Professional judgment must be used in implementing the recommendations of the guide.
True
True or False: The IACUC plays a central role in interpretation, implementation, oversight and evaluation of the institutional animal
care and use program.
True
Who published the Three R’s and in what year?
W.M.S Russell and R.L. Burch in 1959
Practical statements of collective wisdom, convention, or management direction that are internal to the entity are:
a. policy
b. principles
c. procedures
a. policy
Accepted generalizations about a topic that are frequently endorsed by many and diverse organizations are:
a. policy
b. principles
c. procedures
b. principles
True or False: Establishing standard operating procedures can assist and institution in complying with regulations, policies and principles as well as with day-to-day operations and management.
True
True or False: In most situations, the Guide is intended to provide flexibility so that institutions can modify practices and procedures with changing conditions and new information.
True
A standard or guideline that specifies in detail a method, technology or technique for achieving a desired outcome is a ______ standard
a. engineering
b. practice
c. performance
a. engineering - they are prescriptive and provide limited flexibility for implementation
A standard or guideline that provides for flexibility in achieving a desired outcome by allowing professional judgment is a ___ standard
a. engineering
b. practice
c. performance
c. performance
An approach that has been demonstrated, over time, to be beneficial to complete a task or process through the exercise of professional judgment by qualified experienced individuals is a ____standard.
a. engineering
b. practice
c. performance
b. practice
Detailed step-by-step processes meant to insure the consistent application of institutional practices are
a. policy
b. principles
c. procedures
c. procedures
