The Endocrine system Flashcards

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1
Q

What is the Endocrine system?

A

The hypothalmus controls the pituitary gland. the pituitary gland secretes numerous hormones via the blood to control activity of certain organs. it is for long distance communication.

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2
Q

How do steroid hormones communicate ?

A

They are water soluble. they can diffuse across the plasma membrane.

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3
Q

How do protein hormones communicate?

A

They can not diffuse across the plasma membrane. They bind to receptors on the plasma membrane and raise the concentration of cAMP. cAMP then activate the activity of the cell

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4
Q

What are the different sections of the pituitary gland?

A

Anterior gland

Posterior gland

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5
Q

How does the hypothalamus control the pituitary gland?

A

1) it secrets releasing factors into thea portal system to the anterior pituitary
2) the hypothalmus has neurosecretory cells that secrete hormones Vasopressin and Oxyticin directly into the posterior pituitary.

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6
Q

which Hormones are secreted by the anterior pituitary?

A

1) Growth Hormone
2) thyroid stimulating Hormone (TSH)
3) Adrenocorticotropic Hormone (ACTH)
4) Prolactin
5) Follicle stimulating Hormone (FSH) or Intestinal Cell stimulating Hormone (ICSH)
6) Luteinizing Hormone

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7
Q

What are the Hormones secreted by the posterior pituitary?

A

1) Vasopressin or Anti-diuretic Hormone(ADH)

2) Oxytocin

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8
Q

What is the function of Growth Hormone?

A

Causes growth of the body; all cells in all body parts. Important for growth in the adolescent stage. post adolescence it continue to play a role in metabolism (protein synthesis and increasing blood glucose concentration

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9
Q

What are defects of touch/little growth hormone?

A

To much at an early age lead to gigantism

to little leads to dwarfism

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10
Q

What is the function of Thyroid stimulating Hormone (TSH)?

A

stimulate the thyroid gland. thyroxine T4 and triiodothyronine T3 is secreted by the thyroid. It increases the overall metabollic rate of the body

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11
Q

what is the function of Adrecorticotropic Hormone(ACTH)?

A

stimulates production of cortisol by the adrenal cortex.

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12
Q

What is the function of Prolactin?

A

Plays a role in development of the breast after pregnancy and the secretion of milk after child birth

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13
Q

What is the function of Antidiuretic Hormone?

A

also called vasopressin causes rise in the arterial pressure and enhances the rate of water reabsorption by the renal tubules.

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14
Q

What is the function of Oxytocin?

A

Contraction of the uterus and other smooth muscles. Makes milk flow by stimulating myoepithelial cells in the breast

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15
Q

Where is the adrenal gland located?

A

oTop of the kidneys

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16
Q

What hormones are secreted by the adrenal cortex?

A

1) Mineralocorticoids- e.g. aldosterone
2) Glucocorticoids - e.g. cortisol
3) Sex hormones - e.g. testosterone and estrogen

17
Q

What transmitter is secreted by the adrenal cortex?

A

epinephrine (adrenaline)

norepinephrine (noradrenaline)

18
Q

What is the function of the Mineralocorticoids?

A

Regulation of electrolyte balance of the body

it promotes the retention of sodium and the secretion of potassium in the urine.

19
Q

What is the function of the Glucocorticoids?

A

Influence metabolism of fats, proteins and sugar.
concentration of glucose in the blood rise by decreasing the uptake of sugar by the cells
degradation of proteins and the increase of the use of fat for energy.

20
Q

What is the purpose of the sex hormones?

A

Responsible for the differentiation af the sex organs in the males and females.

21
Q

Where is the thyroid gland located?

A

anterior of the neck

22
Q

explain the anatomy of the thyroid gland.

A

it is composed of follicles lined with thyroid glandular cells. they produce a thyroglobulin which contain thyroxin a thyroid molecule.

23
Q

What does thyroxine do?

A

Combines with plasma proteins. they increase the synthesis of proteins and the number of mitochondria in the cell. Which increase the production of ATP. promotes cellular metabolism.

24
Q

What is hyperthyroidism?

A

Excess thyroid secretion. This causes a increased metabolic rate.

25
Q

what is hypothyroidism?

A

Inadequate amounts of thyroid hormones. This causes a slower metabolism and collection of fluid in tissue. This is called myxedema.

26
Q

What are the affect of the thyroid and parathyroid gland?

A

Thyroid produces calcitonin. inhibits osteoclast activity and osteoblasts to form bone tissue. (decreases blood calcium levels)

parathyroid produces parathyroid hormone (PTH) stimulates osteoclasts to breakdown bone. Raising Calcium and PO43- in the blood

27
Q

What are the functions of the pancreatic hormones?

A

It contains clusters of cell(islets of langerhans).
alpha cells -secrete glucagon. increases blood glucose concentration by promoting the conversion on glycogen to glucose in the liver (glyogensis). (gluconeogensis) - production of glucose from amino acids

beta cells - produce insulin. insulin decreases blood glucose by increasing cellular uptake of glucose.

28
Q

What are the hormones of the kidneys?

A

renin & erythropoietin.

29
Q

What does renin do?

A

produces the increase of water absorption and blood pressure through the the activation of the RENIN-ANGIOTENSIN SYSTEM

30
Q

What does the Renin Angiotensin System produce?

A

produces angiotensin II from angiotensin I

angiotensin II - acts on the adrenal cortex to produce and release aldosterone.

31
Q

What is the purpose of Erythropoietin?

A

increase the production of erythrocytes in the red blood marrow. this is essential for the production of vitamin D