The CV system Flashcards

1
Q

what are the 3 components of the CV system

A

blood
heart
blood vessels

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2
Q

what is the path of O2 and nutrients

A

blood
interstitial fluid
body cells

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3
Q

what is the path of CO2 and waste

A

body cells
interstitial fluid
blood

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4
Q

what are the general functions of the CV system

A

transportation
regulation
protection

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5
Q

what does the CV system transport

A
O2
CO2
nutrients
heat
waste
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6
Q

what does the CV system regulate

A

ph
body temp
water content of cells

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7
Q

how does the CV system protect

A

clotting
phagocytosis
antibodies

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8
Q

what forms the blood

A

plasma (55%) + formed elements (45%)

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9
Q

what is important for the blood’s viscosity

A

water (91.5% of blood plasma)

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10
Q

what composes the blood plasma

A
  1. 5% of water

8. 5% of solutes that are mostly plasma proteins

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11
Q

what are the 3 important plasma proteins in the blood plasma

A

albumin (#1)
globulins (antibodies)
fibrinogen

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12
Q

what is the role of albumin

A

transports fatty acids

helps keep H2O from diffusing out of the blood

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13
Q

what is the role of globulins

A

produced during certain immune responses, stimulated by foreign invaders like bacteria and viruses

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14
Q

what is the role of fibrinogen

A

essential for blood clotting

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15
Q

what are the formed elements of the blood

A

99% RBC

1% WBC and platelets

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16
Q

what is hemopoiesis

A

formation of blood cells that happens in the red bone marrow

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17
Q

when does the yellow bone marrow form RBCs

A

in emergencies only

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18
Q

what is hematocrit

A

the % of total blood volume occupied by RBC

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19
Q

what is the normal range of hematocrit in males and females

A

females: 38-46%
males: 40-54%

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20
Q

what is anemia

A

significant decrease in hematocrit

low iron

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21
Q

what is polycythemia

A

significant increase in hematocrit (increased viscosity)

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22
Q

what are some possible causes for polycythemia

A

tissue hypoxia (body pumps out more RBCs to have more binding sites for O2)
dehydration (decreased BV)
blood doping (increased viscosity)
training in altitude

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23
Q

what is another name for RBCs

A

erythrocytes

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24
Q

what do erythrocytes contain

A

they contain oxygen carrying proteins called hemoglobin (gives blood its red color)

25
at what rate do mature RBCs enter the system
>2 million/second
26
what is the anatomy of and RBC
biconcave disc strong and flexible plasma membrane contain glycolipids which act as antigens lack a nucleus and other organelles
27
what does not having a nucleus mean for the RBc
it does not consume the O2, it only carries it
28
what is the function of an RBC
higly specialized o2 transport (also carries 20 % of CO2) contains hemoglobin helps in BP regulation generate ATP anaerobically
29
what forms hemoglobin
globin (protein) | heme (where O2 binds)
30
what gives the RBC its red color
oxydation of Fe2+
31
what is heme
iron molecules
32
what is the production of RBCs
erythropoiesis
33
what is the process of erythropoiesis
begins in the red bone marrow | usually matures in 1-2 days after passes into the bloodstream
34
what is the life span of an RBC
120 days
35
what happens if the rate of destruction of the RBCs is faster than the rate of erythropoiesis
hypoxia | decreased # of hematocrit
36
what are the causes of hypoxia (3)
high altitude anemia circulatory problems
37
what lacks with anemia and what are the s/s
iron certain amino acids vitamin B12 s/s: fatigue, intolerance to cold, pale skin
38
what does hypoxia stimulates
kidneys to increase the release of erythropoietin
39
what is erythropoietin
a hormone that travels to the red bone marrow to stimulate erythropoiesis to produce erythrocytes
40
what is another name for WBC
leukocytes
41
what is the anatomy of a WBC
contains a nucleus do not contain hemoglobin can be granular or agranular
42
what are the types of WBC (5)
``` neutrophils (60%) lymphocytes (20-45%) monocytes(4-8%) eosinophils(1-4%) basophils (0.5%) ```
43
which WBC are granular
neutrophils eosinophils basophils
44
neutrophils
consume/destroy bacteria
45
eosinophils
role in ending allergic reactions/ parasite infections | found along digestive tube
46
basophils
release histamine in later stages of inflammation
47
which WBC are agranular
lymphocytes | monocytes
48
lymphocytes
role in immunity, react to specific foreign molecules
49
monocytes
transform into macrophage | migrate from blood to tissues (chronic disease, viral infections)
50
what are some general characteristics of WBC
life span: can live for months/years but usually a few days bc will be used during periods of infections only live a few hours
51
what is leukoppenia
abnormal low levels of WBC
52
what is leukopenia due to
radiation, shock, chemotherapy
53
what is leukocytosis
increase in number of WBC
54
what is the function ofWBC
combat pathogens entering the body by phagocytosis leave the bloodstream and enter the area of inflammation increase in number when the is inflammation or an injury
55
t/f wbc return to the bloodstream after fighting inflammation
false
56
what is another name for platelets
thrombocytes
57
describe platelets
do not contain a nucleus aid in stopping blood loss by forming a platelet plug release chemicals which promote blood clotting removed by the system by fixed macrophages in the spleen and the liver
58
what is the life span of a platelet
5-9 days
59
can platelets also adhere to the lining of unhealthy vessels
yes results in scaring, inflammation, atherosclerosis results in unwanted clotting