The Cellular Basis of Life Flashcards
starting point of cell biology
1830s
five (5) important contributors to the cell theory:
- Robert Hooke
- Robert Brown
- Matthias Schleiden
- Theodor Schwann
- Rudolf Virchow
he discovered the cell in his initial observation of plant cell walls in 1665
Robert Hooke
he discovered the nucleus
Robert Browne
colleagues that provided the first clearly stated definition of the cell in 1830s
Mattias Schleiden & Theodor Schwann
he observed plant cells
Matthias Schleiden
he observed animal cells
Theodor Schwann
all living creatures, both ____ and ____, are made out of 1 or more ____
- simple
- complex
- cells
it is the structural and functional unit of life
cell
what statement completed the cell theory
“all cells came from pre-existing cells”
contribution of Rudolf Virchow
the statement that completes the cell theory - “all cells came from preexisting cells”
six (6) tenets of the modern cell theory
- All living organisms are made up of cells.
- Cells are the basic unit of life.
- Cells arise from pre-existing cells.
- Hereditary information is passed from cell to cell.
- All cells have the basic chemical composition.
- Energy flows occur within cells.
cell acts as the _____ between living and non-living organisms
border
increasing complexity of living organisms
- cells
- tissues
- organs
- organ systems
- animals
decreasing complexity of non-living organisms
- cells
- organelles
- membranes
- macromolecules
- simple molecules
- atoms
two (2) broad categories
- Prokaryotic
- Eukaryotic
single-celled organisms of the two domains (bacteria and archaea)
Prokaryotic cells
multicellular organism that possesses a clearly defined nucleus
Eukaryotic cells
four (4) common parts present at both categories
- plasma membrane
- cytoplasm
- genetic material (DNA)
- ribosomes that make protein
part of prokaryotic cells where the genetic material is found
Nucleoid
what is Endosymbiotic theory by Lynn Margulis
it is a theory that suggests that eukaryotic cells evolved from prokaryotic cells and occurs when a prokaryotic cell engulfs another prokaryotic cell by endocytosis which results to eukaryotic cells
two (2) processes of endosymbiosis
- Primary Endosymbiosis
- Secondary Endosymbiosis
this process of symbiosis involves the uptake of a cyanobacterium by a non-photosynthetic eukaryote
Primary Endosymbiosis
this process of endosymbiosis occurs when a primary plastid alga is ingested by a photosynthetic eukaryote
Secondary Endosymbiosis
(why are cells small?)
small cells have a high ______ to ______ which allows more stuff to move in and out of the cell
surface area to volume ratio
(why are cells small?)
if a cell goes beyond a certain limit, _____ material will be able to cross the membrane fast enough to accommodate increased volume
not enough
four (4) tools used for studying cells
U
C
S/D
E
- Ultracentrifuge
- Compound Light Microscope
- Stereo / Dissecting Microscope
- Electron Microscope
ultracentrifuge separates things by _____
density
this tool is commonly used to separate cell organelles / blood components
Ultracentrifuge
two (2) important properties of a compound light microscope
- Resolving power
- Magnification (about 100-1000x)
general functions of cells
P
P
F
A
A
- provides structure and support
- produce energy
- facilitate growth through mitosis
- aids in reproduction
- allow passive and active transport
three (3) parts of an animal cell
- Plasma membrane
- Nucleus
- Cytoplasm
also called the cell membrane;
found in all cells that separates the interior of the cell from outside environment;
plasma membrane
purpose of plasma membrane
to impede foreign material from entering the cell and prevent the cellular contents from leaking out
two (2) components of membranes
- lipids
- proteins
carbohydrates associated with lipids
glycolipids
carbohydrates associated with proteins
glycoproteins
three (3) ways proteins can be associated with the plasma membrane
- Intrinsic / Integral
- Transmembrane
- Peripheral / Extrinsic
(functions of plasma membrane)
serve as a _____ or border
cellular barrier
(functions of plasma membrane)
plasma membrane _____ cell
defines
(functions of plasma membrane)
plays an important role for _____ and also for _____
- transport
- recognition
cellular membranes are _____ of lipids and protein
fluid mosaics
most abundant lipid in the plasma membrane
phospholipids
phospholipids are _____ molecules, containing hydrophobic and hydrophilic regions
ampiphatic
this model states that a membrane is a fluid structure with a “mosaic” of various proteins embedded in it
Fluid Mosaic Model
who proposed that cell membrane is a mosaic of proteins dispersed within the bilayer, with only the hydrophilic regions exposed to water
singer & nicolson (1972)
what technique supported singer & nicolson’s theory?
Freeze-Fracture Theory
seven types of movement
S
F
O
F
A
E
E
- Simple diffusion
- Facilitated diffusion
- Osmosis
- Filtration
- Active transport
- Endocytosis
- Exocytosis
membrane-bound organelle that contains the genetic material:
serves to maintain the integrity of the cell by facilitating transcription and replication processes;
largest organelle in the cell
Nucleus
double-membrane that surrounds the nucleus
nuclear envelope
nuclear membrane contains the _______
nuclear pore
this is used for importing proteins into the nucleus and exporting RNA’s and proteins from the nucleus
Nuclear Pore (NPC)
everything between the plasma membrane and the nuclear compartment
Cytoplasm
fluid portion of the cytoplasm
cytosol
network of protein fibers extending throughout the fluid cytoplasm
cytoskeleton
supports and give structure for the cell;
very dynamic and undergo remodeling
cytoplasm
cytoplasm is usually ____ in color
colorless
organelles
- mitochondria
powerhouse of the cell as it is the site of respiration
mitochondria
compartments of mitochondria:
I
O
M
I
- Inner membrane
- Outer membrane
- Matrix
- Intermembrane space
includes the respiratory chain and ATP synthase
inner membrane
invaginations
cristae
permeable to larger molecules
Outer membrane
contains enzymes, mitochondria DNA
Matrix
space between the inner and outer membranes of the cell
Intermembrane cells
two (2) mitochondrial envelopes:
- Inner membranes
- Outer membranes
protein synthesis happens in the ________
matrix
mitochondria is inherited from the _____, while nuclear DNA is inherited from ________
- mother
- both parents
mitochondria is derived from the ______ of the egg cell during fertilization
cytoplasm
four (4) endomembrane systems
E
G
V
L
- Endoplasmic reticulum
- Golgi Apparatus
- Vesicles
- Lysosomes
system of tubes and chambers formed by membranes involved in synthesis, modification, processing & packaging of cellular lipids and proteins
Endomembrane systems
3 kinds of cytoskeleton
M
M
IF
- Microtubules
- Microfilaments
- Intermediate Filaments
three functions of cytoskeleton
S
M
R
- support
- motility
- regulation
protein subunits of microtubules
tubulin
protein subunits of microfilaments
actin
protein subunits of intermediate filaments
keratin
centrosome and centrioles are only located in ____ cells
animal cells
a microtubule organizing center
centrosome
each centrosome consists of how many centrioles?
2 centrioles
groups of cells that are similar in structure and function
tissues
four (4) types of tissues
- Epithelial tissues
- Connective Tissues
- Muscle tissues
- Nervous tissues
lines body cavities
epithelial tissues
five (5) classifications of epithelial tissues:
- Simple Squamous Epithelium
- Simple Cuboidal Epithelium
- Simple Columnar Epithelium
- Pseudostratified Columnar Epithelium
- Stratified Squamous Epithelium
2 classifications of connective tissue
- Connective tissue proper
- Special Type of Connective Tissue
2 categories of connective tissue proper
- Loose connective tissue
- Dense connective tissue
types of loose connective tissue:
- areolar
- adipose
- reticular
types of dense connective tissue:
- Regular
- Irregular
- Elastic
types of special connective tissue
- cartilage
- osseous bone
- blood
concerned with contraction and movement
muscle tissues
categories of muscle tissues
- skeletal muscle
- cardiac muscle
- smooth muscle
functions: transmission of signals
nervous tissue
cells of nervous tissue
neurons