The Brain III Flashcards

1
Q

In the brain, starting with the periosteum, what are the layers, including spaces

A
Periosteum
Dura mater
Subdural space
Arachnoid membrane
Subarachnoid space
Pia Mater
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2
Q

The subdural space is filled with _____ while the subarachnoid space has ______.

A

Interstitial fluid

CSF

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3
Q

In the spinal cord, starting with the periosteum, what are the layers, including spaces

A
Periosteum
Epidural space
Dura mater
Subdural space
Arachnoid membrane
Subarachnoid space
Pia Mater
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4
Q

What fills the epidural space?q

A

Fat and Loose CT

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5
Q

CSF circulates _________ and ________ the CNS.

A

Inside

Outside

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6
Q

Name the three ways CSF protects the brain

A

Mechanical
Chemical
Circulation

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7
Q

How the CSF protect the brain mechanically?

A

CSF is a shock absorbing fluid

Protects delicate tissue from jolts

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8
Q

How does CSF protect the brain chemically?

A

Provides the optimal chemical environment for brain tissue

The brain needs a specific tonic balance

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9
Q

What does the circulation of CSF do for the brain?

A

Its a medium for the exchange of nutrients and waste between blood and nervous tissue

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10
Q

To maintain homeostasis, CSF must be _________ at the ______ _______.

A

Reabsorbed

Arachnoid villi

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11
Q

The arachnoid villi are _______-like projections into the ______ ______ _______.

A

Finger

Superior sagittal sinus

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12
Q

CSF reabsorption only happens at the:

A

Arachnoid villi of the superior sagittal sinus/

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13
Q

What flows in the sinus of the dura mater?

A

Venous blood to the neck veins

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14
Q

What are the 5 dural sinuses beachy wants us to know?

A
Superior sagittal sinus
Inferior sagittal sinus
Straight sagittal sinus
Transverse sagittal sinus
Sigmoid sagittal sinus
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15
Q

In some places, the meningeal dura mater extends inwards to form flat _____ that anchor the brain to the skull.

A

Septa

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16
Q

The brain and spinal cord ______ in the bony cranium

A

“Float”

17
Q

Using a car as an analogy, dura mater is like a ________, and the CSF is like an ______.

A

Seat belt

Air bag

18
Q

Name the sinus in the falx ceribri

A

Superior sagittal sinus

Inferior sagittal sinus

19
Q

What is hydrocephaly?

A

An abnormal accumulation of CSF in the brain that puts pressure on the brain

20
Q

In an infant, hydrocephaly can be treated how?

A

The installation of a shunt

21
Q

Meningitis is prevalent in this population and is caused by:

A

3-mo to 2 years

A variety of bacteria or viruses

22
Q

Meningitis invades the _____ following an infection of the ______ or _____.

A

CNS

Nose or throat

23
Q

Sx of meningitis include:

Diagnosis comes from:

A

Sx: high fever, stiff neck, intense headache

CSF examined for bacteria or WBC

24
Q

The blood brain barrier consists of what 3 layers?

A
  1. Endothelium with tight junctions
  2. Basement membrane
  3. Perivascular feet of astrocytes
25
Q

In the BBB what are responsible for chemical secretion?

A

Astrocytes

26
Q

The BBB is highly permeable to:

A

Water, glucose, lipid-soluble substances: O2, CO2, Alcohol, caffeine, nicotine, anesthetics, heroin

27
Q

The BBB is not permeable to:

A

proteins, antibiotics

28
Q

How do clinicians get drugs past the BBB to the brain area?

A

Precursors or nasal sprays through the nasal area

29
Q

How do clinicians treat Parkinson’s in regards to getting meds through the BBB?

A

Patients need dopamine, which cannot pass through the BBB. L-dopa, precursor to dopamine, is prescribed as it can cross the BBB.

30
Q

At rest, the brain consumes _____% of the O2 breathed in.

A

20%

31
Q

In most cases, a 1-2 min interruption in O2 puts the patient in a state of ____________, after 4 min the patient is __________ __________.

A

Unconscious

Brain dead