Tetracyclines

Question 1

Name an example of a tetracylcine?

Answer 1

1. Doxycycline

Question 2

What organisms are tetracylcines effective against?

Answer 2

Very broad

• Gram +
• Gram -
• Aaerobes

Question 3

Which organisms are tetracyclines not effective against?

Answer 3

Pseudomonas or Proteus

Question 4

Main clinical uses of Doxycycline?

Answer 4

1. Alternative to penicillin for soft tissue infection in the event of MRSA or allergy
2. Atypical pneumonia - mycoplasma/chlamydia

Question 5

Major side effects (3)

Answer 5

1. Photosensitivity
2. Deposits in teeth and bone - contraindic in infants and pregnancy
3. Depresses GUT flora - GI upset