Chloramphenicol Flashcards
1
Q
Mechanism of action
A
Binds to 50s subunit of ribosome and inhibits proteinsynthesis
2
Q
What is Chloramphenical the last resort drug for?
A
- Haemophilius influenza
2. Meningitis
3
Q
What is Chloramphenicol effective against?
A
Typhoid fever
4
Q
What spectrum does it cover?
A
Very broad spectrum
5
Q
Major side effects of Chloramphenicol?
A
- Bone marrow depression
- Pancytopenia
- Fatal aplastic anaemia
