Quinolones Flashcards
1
Q
Give examples of a Quinolone?
A
- Ciprofloxacin
2
Q
How do Quinolones work?
A
Inhibit DNA gyrase
3
Q
What is Ciprofloxacin used for?
A
- 2nd line in Pyelonephritis Tx
- Abdominal infection - 2nd line in Ecoli Tx
- Sepsis in penicillin allergy
4
Q
What type of organisms if ciprofloxacin most effective against?
A
Gram - organims
5
Q
Major side effects of ciprofloxacin (2)
A
- Achillies tendonitis
2. Lowers seziure threshold
6
Q
Are fluoroquinolones bacteriostatic or bactericidal?
A
Bactericidal
7
Q
Which kind of antibiotic are fluoroquinolones?
A
Broad-spectrum
8
Q
Which antibiotics are broad-spectrum
A
Cephalosporins
Fluoroquinolones
9
Q
Which is the only antibiotic that can be given orally to treat pseudomonas infection?
A
Fluoroquinolones
10
Q
How are fluoroquinolones excreted?
A
Urine
11
Q
What is the only use for levofloxacin?
A
Severe community acquired pneumonia in penicillin allergic patients
