Tetracyclines Flashcards
1
Q
What are MOA for tetracyclines
A
inhibit protein synthesis at 30S
2
Q
What are bacterias MOR for tetracyclines
A
porin channels
drug efflux
altered target binding
enzyme inactive
3
Q
What are the tetracycline drugs
A
Doxycycline
100 mg bid x 7- 10 days
4
Q
What does tetracycline treat
A
Strep Staph H flu Neisseria M Cat Ecoli Klebsiella B Frag Clostridium Listeria Mycoplasma Chlamydia Legionella Rickettsiae Borrelia burgdorferi
5
Q
What are common uses for tetracycline
A
DOC - lyme disease Respiratory infections Genital infections Systemic infections H pylori
6
Q
What are adverse effects of tetracycline
A
< 8 age GI upset photosensitive diarrhea hypersensitive to self preg don't use with calcium, aluminum, iron
