Fluoroquinolones Flashcards
1
Q
What is the fluoroquinolone MOA
A
inhibit DNA replication
2
Q
What is bacterias MOR to fluoroquinolone
A
efflux pump
gene mutations
permeability
3
Q
What are the types of fluoroquin
A
2nd gen - ciprofloxacin - ofloxacin 3rd gen - levofloxacin 4th gen - moxifloxacin
4
Q
What does Fluoroquin not treat
A
MRSA
B. fragilis
5
Q
What other bacteria does fluoroquin treat
A
atypical pneum
H. pylori
6
Q
What are common uses for fluoroquin
A
UTI
CAP
complicated G -
7
Q
What are adverse effects of fluoroquin
A
No pregnancy hypersensitive to self no children N/D CNS warfarin