Fluoroquinolones Flashcards

1
Q

What is the fluoroquinolone MOA

A

inhibit DNA replication

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2
Q

What is bacterias MOR to fluoroquinolone

A

efflux pump
gene mutations
permeability

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3
Q

What are the types of fluoroquin

A
2nd gen
- ciprofloxacin
- ofloxacin
3rd gen
- levofloxacin
4th gen
- moxifloxacin
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4
Q

What does Fluoroquin not treat

A

MRSA

B. fragilis

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5
Q

What other bacteria does fluoroquin treat

A

atypical pneum

H. pylori

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6
Q

What are common uses for fluoroquin

A

UTI
CAP
complicated G -

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7
Q

What are adverse effects of fluoroquin

A
No pregnancy
hypersensitive to self
no children
N/D
CNS
warfarin
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