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Z A Pharm III > Penicillins > Flashcards

Penicillins Flashcards

1
Q

What is MOA penicillin

A

inhibit cell wall formation

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2
Q

What is bacteria MOR for penicillin

A

B-lactamase inactivates B-lactam

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3
Q

What are the penicillin types

A 
Narrow spectrum pen
Penicillinase-Resistant Pen (anti-staph)
extended spectrum pen
- amino-penicillins
- anti-pseudomonal penicillins
- B-lactamase inhibitor combos
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4
Q

What penicillins fight strep bacteria

A

all

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5
Q

What penicillins don’t work on staph bacteria

A

Narrow spectrum

amino-penicillins

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6
Q

what penicillins work on MRSA

A

none

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7
Q

What penicillins don’t work on Enterococcus

A

Penicillinase-resistant

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8
Q

What penicillins don’t work on H. flu

A

Narrow

Penicillianse-resistant

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9
Q

What penicillins don’t work on Neisseria

A

Penicillinase-resistant

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10
Q

What penicillins work on M. Cat

A

Amino-penicillin & B-lactamase inhibitors
antipseudomonal penicillins
anti-pseudomonal penicillin & B-lactamase inhibitors

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11
Q

what penicillins don’t work on EKPs

A

Narrow

penicillinase-resistant

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12
Q

what penicillins work on ESPs

A

antipsudomonal & B-lactamase inhibitors

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13
Q

what penicillins work on pseudomonal aeurginosa

A

antipseudomonal

antipseudomonal & B-lactamase inhibitors

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14
Q

What pencillins work on B. frag

A

Amino-penicillin & B-lactamase inhibitors

anti-pseudomonal penicillin & B-lactamase inhibitors

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15
Q

What is the narrow spectrum penicillin and common uses

A

Penicillin V

  • Strep pharyngitis
  • Syphilis (Treponema pallidum)
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16
Q

What is the penicillinase-resistant penicillins and common uses

A

Nafcillin
Dicloxacillin
- skin infections due to staph

17
Q

what are the amino-penicillins and common uses

A

amoxicillin
- otitis media
ampicillin

18
Q

what are the amino-penicillins & B-lactamase inhibitor and common uses

A

Amoxicilin/Clavulanate

- anaerobic infections

19
Q

What are the anti-pseudomonal penicillins

A

piperacillin

ticarcillin

20
Q

What are the anti-pseudomonal penicillins & B-lactamase inhibitor and common uses

A

piperacillin-tazobactam

- empiric broad spectrum coverage

21
Q

What are penicillin adverse effects

A

diarrhea
allergic reaction - rash
neutropenia
thrombocytopenia

22
Q

What are penicillin contraindications & clinical issues

A

hypersensitive to PCN
renal dysfunction
strep pneumo resistant to pen
MIC > 50% for penicillin success

23
Q

What penicillins work on atypicals

A

none

Z A Pharm III (17 decks)

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