Tetracyclines

Question 1

Who should avoid terracyclines

Answer 1

Pregnancy
Breastfeeding
>12

Question 2

Tetracycline moa

Answer 2

inhibit protein synthesis

Question 3

What trimester causes discolouration of teeth

Answer 3

Especially in 2&3rd

Question 4

Minoycline specific side effect

Answer 4

Lupus like syndrome - swollen joints, fever, rash, swelling

irreversible pigmentation (dark blue grey)

Question 5

Side effects of tetracycline

Answer 5

N&V
Visual disturbances and blurriness due to intercranial htn
Photosensitivity
Headache - intercrania htn
Teeth discolouration
Dysphagia with doxy, mino & tetra

Question 6

Which tetracyclines cause dysphagia

Answer 6

Doxycycline
Tetracycline
Monocycline

So take with food or fluid

Question 7

Why do tetracyclines cause vision disturbances

Answer 7

Cause intercanial HTN which can cause blurry vision

Question 8

What other abx can cause vision disturbances

Answer 8

Quinolones
Telithromycin

Question 9

Which tetracyclines avoid sunlight

Answer 9

Doxycycline
Demecocycline

Question 10

Which tetracyclines to avoid antacids with

Answer 10

All so leave 2 hour gap before and after to take tetracycline

Question 11

Contraindications of tetracyclines

Answer 11

Under 12
Pregnancy
Myastehnia gravis
Tendon disorders
Hepatic and renal impairment

Question 12

What to monitor after 6 months use of mincocycline

Answer 12

More than 6 months use then monitor:
hepatic
Pigmentation
Lupus side effects

Every 3 months