Testis, Scrotal Sac, and Epididymis Diseases Flashcards
Testicular tumors are most often of what origin?
Germ cell
Malignant testicular tumors are often of what origin?
Germ cell
Benign testicular tumors are often of what origin?
Sex cord-stromal tumors
What is the most common testicular cancer?
Seminoma
What is the most common risk factor for developing a testicular cancer?
Cryptorchidism
Testicular cancer most often metastasis to what lymph nodes?
Para-aortic
Detail the age at which following tumors are commonly seen: seminoma, embryonal carcinoma, yolk sac tumor, choriocarcinoma, teratoma.
Seminoma- young men and men >65 Embryonal carcinoma- Young men Choriocarcinoma- Young men Yolk sac tumor- Children under 4 Teratoma- all ages
What age range does the spermatocytic seminoma variant typically occur in?
Older individuals
Are most testicular tumors pure or mixed?
Mixed (60%)
Of pure testicular tumors, what is the most common type?
Seminoma
Describe the biphasic appearance of a seminoma.
Neoplastic cells resemble spermatogonia
Lymphocytic infiltrate
Describe the gross appearance of a seminoma.
Fish flesh appearance
Compare the chemosensitivity of embryonal carcinoma to teratoma.
Embryonal carcinoma is chemosensitive Teratoma is chemoresistant
A teratoma of the testes has squamous cells present, what risk does this confer in terms of prognosis.
Teratomas have the potential to undergo malignant transformation, thus, squamous cells may develop into SCC
Cysts are a common feature of what type of testicular tumor?
Teratoma