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Life Cycles > Ovarian Disorders > Flashcards

Ovarian Disorders Flashcards

1
Q

What part of the ovary is exposed to the peritoneum?

A

Surface epithelium

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2
Q

What is a corpus albicans?

A

Ovarian scar composed of connective tissue that forms after the corpus luteum degenerates

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3
Q

Where do most ectopic pregnancies occur?

A

Fallopian tube

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4
Q

What is the most common site of endometriosis?

A

Ovary

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5
Q

What is the gross appearance of ovarian endometriosis?

A

Chocolate cyst

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6
Q

How are BRCA1/BRCA2 related to cancer?

A

DNA repair genes

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7
Q

What are the 4 categories of ovarian surface epithelium tumors?

A

Serous
Mucinous
Endometrioid
Clear cell

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8
Q

What is the histologic appearance of an ovarian serous borderline tumor?

A

Hierarchical branching

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9
Q

A laminated/targetoid calcification is seen on histologic examination of a serous cystandenocarcinoma. What is the term given to this finding?

A

Psammoma bodies

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10
Q

What is the most common ovarian malignancy?

A

Serous cystadenocarcinoma

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11
Q

If an ovarian tumor has invaded the stroma is it a borderline tumor or a carcinoma?

A

Carcinoma

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12
Q

Clear cell carcinoma of the ovary is associated with what pathologic condition?

A

Endometriosis

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13
Q

Once resected granulosa cell tumors can be followed using what serum marker?

A

Inhibin

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14
Q

Call-Exner bodies are pathognomonic for what tumor?

A

Granulosa cell tumor

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15
Q

A signet ring cell is noted on a pathology report of a biopsied ovary. What type of tumor is this?

A

Krukenberg tumor- metastatic gastric carcinoma

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16
Q

What are the most common causes of anovulation?

A 
Athletes
Adrenal insufficiency
Cushing syndrome
Eating disorders
Hyperprolactinemia
Obesity
Pregnancy
PCOS
Premature ovarian insufficiency
Thyroid disorders
17
Q

What is the LH:FSH in a woman with PCOS?

A

Increased

18
Q

What is the most common ovarian mass in young women?

A

Follicular cyst

19
Q

Theca-lutein cyst are associated with what neoplasitc conditions?

A

Choriocarcinoma

Hydatidiform mole

20
Q

What is the most common adnexal mass in a woman >55?

A

Ovarian neoplasm

21
Q

Ovarian neoplasms can arise from what 3 origins?

A

Surface epithelium
Germ cells
Sex cord stromal tissue

22
Q

What decreases risk for ovarian neoplasms?

A

Pregnancy
Breast feeding
OCPs
Tubal ligation

23
Q

What tumor marker can be used to monitor progression of ovarian cancer?

A

CA 125

24
Q

Mucus secreting epithelium lines what benign ovarian neoplasm?

A

Mucinous cystadenoma

25
Q

What is the most common benign ovarian neoplasm?

A

Serous cystadenoma

26
Q

What is the most common ovarian tumor in women 20-30 years old?

A

Mature cystic teratoma

27
Q

What tumor has coffee bean nuclei on H&E stain?

A

Brenner tumor- looks like bladder

28
Q

What is Meigs syndrome?

A

Ovarian fibroma
Ascites
Hydrothorax

29
Q

Are mature or immature teratomas malignant?

A

Immature

30
Q

Is a mature or immature teratoma more likely to contain thyroid tissue?

A

Mature

31
Q

Is a mature or immature teratoma more likely to contain neural-like tissue?

A

Immature

32
Q

What is the most common malignant stromal tumor of the ovary?

A

Granulosa cell tumor

33
Q

hCG and LDH are tumor markers for the most common ovarian tumor in adolescents. What is the type of tumor?

A

Dysgerminoma

34
Q

A choriocarcinoma can develop during or after pregnancy in the mother or baby. What is the tissue of origin?

A

Trophoblstic tissue- cytotrophoblast/syncytiotrophoblast

35
Q

Where do choriocarcinomas metastasize?

A

Lungs

36
Q

What is the classic clinical picture of a woman with a choriocarcinoma?

A

Increased hCG
Hemoptysis
Shortness of breath

37
Q

What tumor is associated with Schiller-Duval bodies?

A

Yolk sac tumor

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