Fertilization

Question 1

What cell in the male maintains the gamete pool?

Answer 1

Spermatogonium

Question 2

Are Leydig cells or Sertoli cells temperature sensitive?

Answer 2

Sertoli cells

Question 3

What are the components of a mature spermatozoon?

Answer 3

Acrosome
Head
Neck
Middle piece
Tail

Question 4

What proteins are specialized histones that lead to the very condensed chromatin of a sperm?

Answer 4

Protamines

Question 5

What condition causes infertility due to cilia dysfunction as a result of defective dynein arm defect?

Answer 5

Kartagener syndrome

Question 6

Aside from infertility what other signs/symptoms are associated with Kartegener syndrome?

Answer 6

Situs inversus
Bronchiectasis
Recurrent sinusitis

Question 7

Where does sperm capacitation take place?

Answer 7

Female genital tract

Question 8

Define sperm capacitation.

Answer 8

Process in which spermatozoa acquire the ability to undergo the acrosome reaction and fertilize an egg

Question 9

What layers must a sperm pass through to fertilize an egg?

Answer 9

Corona radiata
Zona pellucida
Oocyte plasma membrane

Question 10

What 3 glycoproteins compose the zona pellucida?

Answer 10

ZP1/2/3

Question 11

What glycoprotein mediates sperm binding to the zona pellucida?

Answer 11

ZP3- binds acrosome ZP3 receptor