Test 4: parturition Flashcards
The physiological processes involved in the birth of offspring which includes the delivery of the fetus and fetal membranes through the vaginal canal and involution of the uterus.
parturition
Processes Involved with Parturition
• Myometrial ___
- ____ of the birth canal
- Maternal abdominal straining
- Expulsion of the fetus
- Expulsion of the ___
- Onset of lactogenesis
- Development of maternal behavior
contractions
Relaxation and dilation
fetal membranes and fluids
how does ACTH affect pregnancy
Increase fetal ACTH
- Elevation of cortisol causes conversion of progesterone → estrogen by placenta
- Estrogens increase and cause the synthesis of PGF-2alpha by the uterus
• Cervix softens • Uterus contracts
___ will decrease and ___ will increase to cause cervix to soften and uterus to contract
progesterone
estrogen
___ cause uterine contractions
PGF2alpha
oxytocin
___ are luteal dependent
doe
sow
bitch
camelids
___ are not CL dependent
will get progestogen from the conceptus
Ewe –after 50 days • Mare –after 60 days • Queen-after 45 days
cortisol in cattle, goats and swine
these are luteal dependent (need CL to produce progesterone throughout the entire pregnancy)
Cortisol stimulates placental estrogen production
- Uterine release of PGF2α
- Rapid luteolysis→ CL dies
- Progesterone decreases
• Cervix relaxation • Uterine contractions
In cattle, goats, and sows, the circulating cortisol stimulates placental estrogen production causing uterine release of PGF-2α and rapid luteolysis of the CL, which results in a rapid decline in progesterone concentrations and subsequent uterine contractions. Cortisol production by the fetus during late gestation is essential for rapid lung maturation and the production of pulmonary surfactant, which is necessary for the survival of the fetus. Also during late gestation, there is an increase in estrogens and relaxin. Along with the rapid decline in progestogens and rise in prostaglandins, uterine contractions occur, the cervix softens and dilates, and parturition results. As the fetus enters the birth canal, The Ferguson Reflex occurs and oxytocin is released from the posterior pituitary. Oxytocin along with PGF-2α causes peristaltic uterine contractions, which result in delivery of the fetus and placenta. Estrogens are important in inducing receptors in the uterine tissue for oxytocin.
___ enzymes are needed to convert progesterone to estrogen(estradiol)
17 alpha hydroxylase
17-20 desmolase
aromatase
hormone profile of cow during parturition
cortisol increases and convert progesterone → estrogen
this causes release of PGF2alpha
progesterone decreases
cervix relaxes and uterine contraction
estrogen causes
secretion of the repro tract
increased contraction → oxytocin
how does PGF2 effect uterus
ferguson reflex
stretching of the cervix causes release of oxytocin which will cause uterus to contract → positive feedback
signs of parturition in cow
Relaxin → Relaxed pelvic ligaments
- Elevated tail head
- Edematous vulva
- Udder development
- “springers” → tail head ligaments relaxed (looks sprung up)
mare impending parturition
Relaxed pelvic ligaments
- Relaxed vulva
- Udder development
- “Waxed” with colostrum → dried beads of colustrum
ewe impending parturition
relaxed ligament
udder development
(shear before lactation)
presentation longitudinal
fetus spine parallel to mothers
can be anterior or posterior (head or feet first)