Test 4- Anatomy 2 Renal Block Flashcards
Vocabulary/Abbreviations
- _____: in to something
- _____: out of something
- PCT: _____
- LOH: _____
- DCT: _____
- JGA: ______
- Afferent
- Efferent
- Proximal convoluted tubule
- Loop of Henle
- Distal convoluted tumble
- Juxtaglomerular apparatus
Functions of the kidneys
- Regulate blood ______
- Helps to regulate blood levels of ions like ______, ______, ______, ______, and ______
- Regulate blood ____
- Kidney excrete variable amount of ______ ions into urine and conserve ______ ions, bicarb is important buffer of ____
- Ionic composition
- Sodium/potassium/Calcium/Chloride/Phosphate
- pH
- Hydrogen/Bicarbonate/H+
Functions of the kidneys
- Regulate blood ______: adjust blood volume by conserving or eliminating water into the urine
- Regulate blood ______: kidneys excrete enzyme renin, The is activates renin-Angiotensin-aldosterone pathway; increased renin= increased blood pressure
- Maintain blood ______: separately regulates loss of water and loss of solutes in urine, kidney maintain relatively constant osmolarity close to 3000mOsm/liter
- Volume
- Pressure
- Osmolarity
Functions of the kidney
- Produce certain _____: kidneys produce the hormones calcitriol (active form of vitamin D) erythropoietin (stimulates production of RBC’s) and renin (hormone/enzyme)
- Regulate _____ levels: like the liver, the kidneys can use amino acid glutamine in gluconeogenesis, which can then release new glucose into the blood stream to help maintain Normal level
- Hormones
2. Blood glucose
Functions of the kidneys
- Excrete _________ substances: By forming urine, kidneys help body to get rid of ammonia and urea, Bilirubin, Creatinine, Uric acid. Drugs, environmental toxins
- Wastes and foreign substances
Anatomy of kidneys
- Located in ________ space: anatomically between last thoracic and 3rd lumbar vertebrae, partially protected by the 11th and 12th ribs. Right kidney is slightly lower than left
- The _______ face the spinal column
- Retroperitoneal space
2. Concave medial border (Hilum)
External Anatomy of the Kidney
Three external layers
- _____: outermost layer. Dense connective tissue anchors kidney to surrounding structure and retroperitoneal wall
- _____: Middle layer. Fatty tissue surrounding renal capsule, protection and holds kidney in place in cavity
- _____: Innermost layer. Smooth, transparent connective tissue covering that is continuous with ureters; helps maintain shape of kidney and offers protection
- Renal Fascia
- Adipose Capsule
- Renal capsule
Internal anatomy of the kidney
- ______ : contains all of the glomeruli and convoluted tubles of nephrons. Also makes columns that lay between pyramids
- _____: contains all of the loops of Henle and collecting ducts. Collection of all renal pyramids comprise the medulla
- _____: One portion of the medulla. 8-18 per kidney
- _____: narrow apex of the pyramid. Contains the papillary duct leading to minor calyx
- Cortex
- Medulla
- Pyramid
- Papilla
Internal anatomy of the kidney
- ______: space between renal pyramids. Is a portion of the renal cortex
- _____: a functional region within the kidney. Pyramid (medulla)+ overlying cortex + 1/2 each adjacent column (cortex)
- ______: small chambers that collect urine directly from papilla. 8-18 each kidney
- _____: larger chambers that collect urine from multiple minor calyces. 2-3 each kidney, extensions of ureters
- Columns
- Lobe
- Minor calyx
- Major calyx
Internal anatomy of the kidney
- ____: major calyces drain into one large chambers (pelvis). This mixes/collects all urine from entire kidney. Connects to the ureter outside of the kidney
- ____: The kidney is 3-dimensional, so in between the other structures there are spaces that house some adipose tissue, the blood vessels, and nerve supply
- ____: A region. Indentation of kidney where ureter emerges with blood and lymphatic vessels, and nerves
- Renal pelvis
- Renal sinuses
- Renal hilum
Blood supply
- Renal blood flow is ______ per minute
- _____ per kidney
- Total amount of blood in adult is _______
- Starts at ____ levels and then branches from there into smaller vessels
- This ______ allows for filtration, but not _______
- 1200ML
- 600mL
- 4500-5500mL
- Aortic
- Glomerulus/Reabsorption
Blood supply
1.-16.
- Aorta
- Renal artery
- Segmental artery
- Interlobar artery
- Arcutate artery
- Interlobular artery
- Afferent arterioles
- Glomerulus
- Efferent arterioles
- Peritubular capillaries
- Vasa recta (juxtameduallary nephrons only)
- Interlobular vein
- Arcuate vein
- Interlobar vein
- Renal Vein
- Inferior vena Cavae
Blood
- Blood flows into the ____ to get filtered
- It enters each _____, gets filtered through the ______, and exits the corpuscle to flow into a ______ system
- Blood is filtered in the glomerulus, where things can be _____ only
- When in the ____ capillaries/_____, blood will still act like it does in any other capillary in the body. Stuff will move in and out of the capillaries depending on _______
- This capillary action acts as a ________ filter
- Depending on the body’s needs, it can ______/______ more water/______ as needed
- Kidneys
- Corpuscle/Glomerulus/Capillary
- Removed
- Peritubular/Vasa recta/Pressure
- Secondary filter
- Reabsorb/Secrete/Solutes
Filtrate
Blood flows into the kidneys to get filtered
- As blood flows through, certain substances are removed from blood and placed into the urinary tubular system. This is known as ______
- Filtrate is first found in the _______ capsule
- From there it flows through the _____ and then into _______ ducts
- While in these ducts, things can still be _____ or ______
- Once the filtrate leaves the collecting duct, it is then called _____
- Filtrate
- Glomerular capsule (Bowmans capsule)
- Tubules/Collecting ducts
- Added/Removed
- Urine
The Nephron
- Function unit of the kidney- approximately _____ in each kidney
Nephron consist of two parts:
- ______: where blood is filtered. Glomerulus/Glomerular capsule (aka Bowman’s capsule)
- ______: Filtered contents (from blood; three parts). Proximal convoluted tubule attached to capsule. Loop of Henle (nephron loop)- middle section. Distal convoluted Tubule- distant from capsule, empty into collecting duct
- Corpuscle and both convoluted tubules reside in _____
- Only loop of Henle extends into the renal _____
- One million
- Renal corpuscle
- Renal Tubule
- Cortex
- Medulla
Nephrons
Two different types of nephrons
- ______: 85% of nephrons
- Renal corpuscles lie in ______ of renal cortex
- ____ loops of Henle
- ______ capillaries only
- ______: 15% of nephrons
- Renal corpuscles lie ______ in the renal cortex
- _____ loops of Henle
- Peritubular capillaries that give rise to the _______
- ______: capillary bed that extends into medulla surrounding the Loop of Henle
- Cortical Nephron
- Outer portion
- Short
- Peritubular
- Juxtamedullary nephron
- Deep
- Long
- Vasa Recta
- Vasa recta
Cortical Nephrons
- ______ nephrons
- _____ lie in the outermost portion of the cortex
- ______ limb of loop of Henle barely dips into he renal medulla
- After a hairpin turn, the ______ limb of the loop of Henle returns to the cortex
- Peritubular capillaries: arise from the ______ arterioles. Intermingle throughout the _____ and ______ tubules. These then flow into ________ veins and eventually back into _______ circulation
- Short
- Renal corpuscles
- Descending
- Ascending
- Efferent/Proxmial/Convoluted/Interlobular/Systemic
Juxtamedullary Nephrons
- Long nephrons: Renal corpuscles lie in the _____. ______ limb of loop of Henle dives deep into the renal medulla. Anatomy lends to very ____ and _______ urine. After a hairpin turn, the ascending limb of loop of Henle climbs back to the _____
- Peritubular capillaries: arise from the ______ arteriole. Intermingle throughout the ______ and ______ tubules. In the ________ nephrons only, a specialized capillary system exists coming off of these pretubular capillaries
- Cortex/Descending/Dilute/Concentrated/Cortex
2. Efferent/Proximal/Convoluted/Juxtamedullary
Juxtamedullary Nephrons
Vasa Recta
- Coming from the _____ capillaries, this type of capillary System dives deep into renal medulla
Flows Side by side each of the loops of Henle so that things can
- _____ of the capillaries and into the _____ as well
- ______ of the Filtrate and into the ______
- The design with the use of vasa recta is extremely important for keeping a constant ______ gradient so that things can flow in and out
- Peritubular
- Flow out/Filtrate
- Out of/Capillaries
- Osmotic pressure
Blood flow-Nephron
Afferent arteriole
- The arteriole coming into the _____/_______. Brings blood in for _______
- Wider lumen, thicker walls. Has much more capability to ____ or ____ when compared to ______ arteriole
Glomerulus
- Ball of twine like capillary structure that buds off of the ______ arteriole
- Modified simple squamous epithelial cells called ______
- Podocytes have fingerlike projections that wrap around the _______ capillaries
- Corpuscle/Glomerulus
- Constrict/Dilate/Efferent
- Afferent
- Podocytes
- Glomerular
Blood Flow- Nephron
Efferent arteriole
- The arteriole _______ the corpuscle/glomerulus
- Brings blood with larger solutes into the _______ capillaries and then back into ______ circulation
- Smaller lumen size, thinner walls. Smaller lumen size aids in ______ sometimes needed for _______ filtration
- Leaving
- Peritubular/Systemic
- Back pressure/Glomerular