TCA Flashcards

1
Q

Where is the PDH complex found ? What are the two metabolizing enzymes pyruvate encounters ? What happens when energy charge is low to carboxylase ?

A
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2
Q

The PDH complex is broken down into 3 enzymes which are ? What does the complex require ?

What is the net result ?

A
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3
Q

How is PDH activity regulated ? What happens when it is phosphorylated , and by which enzyme ?

What inhibits PDH kinase vs PDH phosphatase ?

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4
Q

In the adipose tissue, insulin increases what ?

How about cardiac muscle PDH activity increase by ?

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5
Q

What is Arsenic poison? What is it caused by ?

What are the symtoms caused by ?

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6
Q

What is pyruvate dehydrogenase deficiency ?

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7
Q

read

A
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8
Q

What is Citrate synthase for ? The increase levels of citrate in the cytoplasm activate ..

What does it inhibit ?

in non hepatic tissue citrate is required for ?

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9
Q

What is Fluoroacetate Poisin ? what is it used for ? what is it converted in the body ? what does it result ? What are the symptoms ?

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10
Q

What is the purpose of Aconitase and Isocitrate ? Why is it so important ? How is regulated ?

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11
Q

What is the purpose of a-ketoglutarate dehydrogenase complex and succinyl-CoA synthetase ?

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12
Q

What is the purpose of Succinate dehydrogenase, what does it create ? What about fumarate ?

what type L or R

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13
Q

What is malate dehydrogenase ? (MDH) purpose ?

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14
Q

What is the number moleucle produced from one molecule of acetyl CoA

How many NADH, FAD2H,GTP

How amny ATP

mnemonic to remember creb cycle ?

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15
Q

How do you regulate TCA cycle ?

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16
Q

Regulation of the TCA cycle ?

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17
Q

What are major regulatory interactions ?

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18
Q

look

A