Digestion and Transport of Dietary Lipids Flashcards

1
Q

What is a triacyglycerol ? What is the purpose ?

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2
Q

What are the TAG hydrolyzes to, and where ?

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3
Q

What is bile salt? What is it made of? what does it do ? what acts on the gallbladder?

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4
Q

What is pancreatic lipase for ? What does it break ?

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5
Q

The pancreatic lipase , what happens in response to acidic material ? What does secretin singal ? What is the purpose of bicarbonate ? What is the purpose of colipase ? What is the role of lipase ?

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6
Q

What is a orlistat ? What does it inhibit ?

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7
Q

know this

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8
Q

What is short and medium chain fatty acids influence with bile salt ? Where are they absorbed? Where does it enter and how is it transported to the liver ?

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9
Q

Know this

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10
Q

What are chylomicrons ? What happens after lipase hydrolyzes ?

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11
Q

What are chylomicrons composed of ?

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12
Q

How are chylomicrons transported ?

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13
Q

know the fate of chylomicrons ?

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14
Q

know the absorption of food lipids

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15
Q

What is the major source of carbon for the synthesis

of fatty acids ? Where does it occur? what is glucose converted ? What does the product useful for ?

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16
Q

What is the conversion of glucose to Acetyl -CoA ? Where does it begin ?

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17
Q

What happens to the acetyl CoA are high ? What is citrate cleaved from , and what does form? What is the role of pyruvate dehydrogenase ? What is the role of NADPH required for ?

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18
Q

How are Oxaloacetate is converted to pyruvate ? What are the two stops ?

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19
Q

What is the formation of malonyl-CoA for ? What is the purpose of Acetyl CoA carboxilase enzyme

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20
Q

Know the regulation of Acetyl - CoA carboxylase ?

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21
Q

What does prolong consumption of a diet containing excess calories cause ?

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22
Q

For the synthesis of long chain fatty acids, what happens when malonyl -coA synthesized ?

What happens to each passage through the cycle ?

What happens when the chain reaches 16 carbons ?

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23
Q

For Fatty acid synthase complex , the large enzyme composed of ?

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24
Q

For Fatty acid Synthase complex, what is needed to initiate FA biosynthesis ?

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25
Q

In Step 1, Acetyl-CoA is transferred to ?

What does Malonyl-CoA attached to ?

What does acetyl and malonyl moieties condense ?

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26
Q

In step 2, what happens in the b-keto group ?

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27
Q

In the step 3, the elimination of water creates ?

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28
Q

Step 4, the double bond is reduced to ?

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29
Q

In repetition, the 4C fatty acyl chain is

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30
Q

For fatty acids synthesis note, where does it take place ? What are the intermediate attached to?

What happens in higher organism ?

What happens to the activated donor ?

What is fatty acid reduction ? When does it stop?

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31
Q

In elongation, palmiate is activated to form ?

The long chain fatty acids can be elongated in two carbons at ?

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32
Q

Desaturation, where does it occur ? The most common is the placement of ?

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33
Q

The essential fatty acids, the mammals cannot incorporate a ?

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34
Q

What is the Linoleic acid for ? What does it bind to ?

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35
Q

The fate of fatty acids, What happens to most of the FA? what are the two fates ?

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36
Q

Triacylglycerol, where is the glycerol-3-phosphate produced ? Where does glycerol-3-phosphate reacts with ?

what happens to phosphatidic acid ?

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37
Q

For storage, what kind of tissue? Where are LPL digest ? Where do FA enter ?

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38
Q

Release, what happens in lipolysis ? What is hormone sensitive lipase ?

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39
Q

For release of fatty acids, what does it utilize ? What does it activate ? know it

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40
Q

.

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41
Q

To release of fatty acids know it

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42
Q

The B-Oxidation of fatty acids, is a process by which fatty acids are degraded by ?

The B-Oxidation occurs in the ?

The 2-C units are released as ?

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43
Q

Activation of Fatty acids, the Acyl-CoA synthease condenses ?

The formation of a Coa ester is ?

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44
Q

Transport of Fatty acids into Mitochondria, where does B-Oxidation occur ?

Where are Acyl-CoA are converted to ?

The translocator then imports ?

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45
Q

In Deficiencies of Carnitine of Carnitine transferase or translocator, What are the symptoms include ? What tissue and organ does it effect ?

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46
Q

For B-Oxidation of fatty acids it involves ? Fatty acid oxidase are found in ?

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47
Q

Acyl-CoA Dehydrogenase, what does the mechanism involves ?

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48
Q

For Enoyl-CoA Hydratase, what is the water for ? What does it use the substrate with ?

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49
Q

Hydroxyacyl-CoA dehydrogenase, oxidizes tge B-Hydroxyl group to ?

The enzyme is completely specific ?

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50
Q

In thiolase, the nucleophilic sulhydryl group of CoA-SH attaks the ?

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51
Q

The B-Oxidation, the four steps of B-Oxidation are repeate to get FA ?

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52
Q

Generation of ATP

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53
Q

B-Oxidation of Odd Chain FA, the odd chain fatty acids are less ?

The B-Oxidation occurs pretty much ?

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54
Q

B-Oxidation of Unsaturated FA

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55
Q

know it

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56
Q

Ketone bodies what is it for?

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57
Q

know it

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58
Q

know this

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59
Q

Ketone bodies and Diabetes are ?

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60
Q

know this

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61
Q
A