gluconeogenesis Flashcards

1
Q

What is gluconeogenesis ? What is gucose is the major source of fuel for ? After overnite fasting where is it used ?

What happens during prolonged fasting kidndey which organ provides most of the glucose ?

Where is glycerol come? lactate ? and amino acid ?

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2
Q

During fasting where is glucuse produced ? how about prolong fasting ?

When is glycogenolysis and gluconeogenesis used ?

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3
Q

Are glycolysis reactions freely reversible , what are they used for ? What happens to the remaining reactions

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4
Q

What are the major precursor for gluconeogenesis ?

What are the enzymes ?

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5
Q

What is lactate Dehydrogenase Deficiency ? What are the symptoms ?

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6
Q

know this !

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7
Q

What is different from glycolysis and glucogenesis that makes them not the reverse of each other ? What is the purpose of pyruvate carboxylase, and what does it require ? Where is it located ?

What is the purpose of PEP carboxykinase , where does it happen ? W

What is the purpose of fructose 1,6 biphosphatase ?

What is the purpose of glucose 6 phosphatase ?

What does it produce ?

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8
Q

Explain the pathway of biotin in pyruvate carboxylase ?

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9
Q

What is phosphoenolpyruvate carboxykinase deficiency ? what is the symptoms ?

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10
Q

What is the purpose of fructose 1,6 biphosphatase ? What is important about this ?

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11
Q

What happens when high glucagon/insulin ratio to produce fructose 6-phosphate ?

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12
Q

What is F-1,6 Biphosphatase deficiency ? What is the glucagon effect ? What is the Covalent modification fo the enzyme activity ?

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13
Q

What is Deficiency of F-1-6 Biphosphatase ? Where is it present ? How do you treat people ?

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14
Q

What is the purpose of glucose 6 phosphatase ? What does it bypass ? Where is it present ? where is it absent? How glucose transferred ?

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15
Q

What is Von Gierke Disease (Glycogen Storage diesease ) ?

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16
Q

What is negative nd positive effectors of gluconeogenesis ?

What are the most significant site for control

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17
Q

know this

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18
Q

know this

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19
Q

What is gluconeogenesis controlled by ? What is the role of glucagon or epinephrine do ?

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20
Q
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