Pentose Phosphate Pathway Flashcards

1
Q

memorize

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2
Q

What does the pentose phoshate pathway utilize glucose 6 phoshpate for ? Where does 30 of the oxidation of glucose occur What is the primary fuction of this pathway ?

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3
Q

What is the second purpose of PPP pathway ? Third ?

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4
Q

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5
Q

Where does the reaction of PPP occur ? What are the arms ? What does hte oxidation step use ? What does it produce ?

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6
Q

What is important about the first reaction (glucose 6 phosphate dehydrogenase )? is it reversible ? What can inhibit it ? What effect does insulin have ?

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7
Q

what is the oxidative stage of the pentose phosphate pathway ?

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8
Q

In the non-oxidative reaction of PPP, what does it generate ? What is equally important ?

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9
Q

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10
Q

In non-oxidative reactons of PPP, the primary enzyme are ? co-factors, and what do they do ? What causes wenicke’s encephalopathy ?

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11
Q

In the non-oxidative reactions of PPP, what is the role of transaldolase ? What is the result ?

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12
Q

Know which enzyme produces what

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13
Q

Why is NADPH important ? What cells need it ? What improtance in making ribonucleotides to deoxribonuclieodes ?

Whats the differnce of NADPH and NADH ?

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14
Q

In Erythrocytes and the PPP,, what is the predomiant pathway of carbohydrate metabolism in red blood cell ?

What does the PPP supply RBC ? What does inability to maintain reduced glutathione in the RBC lead ?

Whats its conenction with NADPH with glutathione ?

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15
Q

Erythrocytes and the PPP,

What effect does oxidants have on RBC ?

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16
Q

memorize

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17
Q

What is NADPH necessary for ? What is NO powerful for ? Where is it elevated ? What does it do to the hair cycle ? and penis ?

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18
Q

know

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19
Q

What is the purpose of the cytochrome p450 monooxygenase system ?

What does metabolize? partiipate ? and improtant in ? Drug metabolism ?

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20
Q

What is glucose 6-phosphate dehydrogenase deficiency ?

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21
Q

What are precipitating factors in g6PD deficiency ?

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