TB Drugs

Question 1

nicotinic acid derivative
BACTERICIDAL
for TB (active, latent, prophylaxis)
MOST IMPORTANT DRUG USED IN TB (FIRST LINE AGENT)
liver metabolism by acetylation
POTENT CYP450 INHIBITOR
less active against other mycobacteria

Answer 1

isoniazid

Question 2

prevent neurotoxicity sec to isoniazid by co-administering what?

Answer 2

pyridoxine (vit. B6)