Hormonal Regulators

Question 1

Recombinant PTH
PHOSPHATE THRASHING HORMONE
must be administered in low intermittent doses to stimulate bone formation

Answer 1

Teriparatide

Can only use up to 2 years
>2 years: risk of osteosarcoma

Question 2

Signs and symptoms of excess PTH?

Answer 2

Painful bones
Renal stones
Abdominal groans
Psychiatric overtones

Question 3

Inactive vitamin D

For vitamin D deficiency

Answer 3

Ergocalciferol

Cholecalciferol

Question 4

Active vitamin D

For SECONDARY HYPERPARATHYROIDISM IN CKD

Answer 4

Calcitriol
Doxercalciferol, Paricalcitol, Calcipotriene

Required in CKD, liver disease, and hypoparathyroidism

Question 5

Thyroid hormone secreted by parafollicular C cells

For Paget’s disease of bone, hypercalcemia, osteoporosis, tumor marker for thyroid Ca

Answer 5

Calcitonin
Salcatonin

Administered as nasal spray