IV Anesthetics

Question 1

IV general anesthetic
ultra-short acting barbiturate
for anesthesia conduction, increased ICP (as it decreases cerebral blood flow)
SE: dependence liability greater than benzodiazepines, acute intermittent porphyria
additive CNS depression with ethanol
POTENT INDUCER OF CYP450 ENZYMES

Answer 1

thiopental

methohexital, thiamylal

Question 2

IV general anesthetic
short-acting benzodiazepine
increases FREQUENCY of Cl channel opening
for anesthesia induction, pre-operative sedation
SE: anterograde amnesia, unwanted daytime sedation, post-operative respiratory depression

Answer 2

midazolam

brotizolam, triazolam, oxazepam, etizolam, lorazepam

Question 3

IV general anesthetic
highly lipophilic
for DISSOCIATIVE ANESTHESIA
SE: emergency delirium

Answer 3

ketamine

Question 4

what can reduce emergence delirium secondary to ketamine?

Answer 4

pre-treatment with benzodiazepines

Question 5

IV general anesthetic
for patients with limited cardiac or respiratory reserve
SE: adrenocortical suppression (impairs aldosterone production)
minimal effects on CV and respiratory functions
NO ANALGESIC PROPERTIES

Answer 5

etomidate

Question 6

IV general anesthetic
interacts with u, o, and k receptors
SE: respiratory depression
neuroleptanesthesia achieved by combining with droperidol and NO

Answer 6

fentanyl

morphine, alfentanil, remifentanil

Question 7

antidote to fentanyl

Answer 7

naloxone

Question 8

IV general anesthetic
for prolonged sedation
SE: bradycardia, hypotension
called the MILK OF AMNESIA
additive effects with sedative-hypnotic drugs

Answer 8

propofol

fospropofol