T5M3

Question 1

How many pairs of chromosomes in a human cell?

Answer 1

23

Question 2

The pairs of chromosomes in a human cell consists of how many base pairs of DNA?

Answer 2

over 3 billion

Question 3

How many protein coding genes in human genome?

Answer 3

estimated over 20 000

Question 4

More than one gene per chromosome: yes or no?

Answer 4

yes

Question 5

Alleles are linked on a single chromosome meaning they must

Answer 5

unlink and recombine in different ways

Question 6

How many types of sex chromosomes? What are they?

Answer 6

2, X and Y

Question 7

How many genes on Y chromosome? Code for how many proteins?

Answer 7

78, code for 25 proteins (half sex)

Question 8

Non Homologous

Answer 8

almost none of the genes in the X chromosome have counterparts in Y chromosome

Question 9

Sex linked gene

Answer 9

a gene on either sex chromosome, expression of phenotype depends on sex of individual

Question 10

Do Mendel’s principles of inheritance apply to genes on X an Y?

Answer 10

no, did not observe in pea plants they have no sex

Question 11

Ishihara colour test

Answer 11

red-green colorblindness, circle filled with dots

Question 12

Women that are colour blind genotype

Answer 12

homozygous for the color blind allele

Question 13

Male colour blind genotype

Answer 13

receives recessive colour blind allele from mother

Question 14

Hemizygous individual

Answer 14

only have one locus for this allele, rule of dominance and recessiveness no longer apply

Question 15

Hemizygous individual

Answer 15

only have one locus for this allele, rules of dominance and recessiveness no longer apply

Question 16

Will a male show phenotype associated with the one allele they carry on X chromosome?

Answer 16

yes

Question 17

Chances of passing on allele that determines colour blindness

Answer 17

50%

Question 18

Haemophillia

Answer 18

blood clotting disorder, X linked recessive trait

Question 19

Mendel’s second law of inheritance tells us that

Answer 19

two genes sort independently during gamete formation

Question 20

Chromosome size

Answer 20

155 megabases/155m base pairs

Question 21

Dystrophin codes for

Answer 21

protein muscle development

Question 22

HPRT1 gene mutation can lead to

Answer 22

arthritis, hemophilia, colour blindness

Question 23

Linked genes

Answer 23

Genes that are positioned close together on same chromosome

Question 24

Will linked genes always be inherited together?

Answer 24

no

Question 25

Recombination of alleles

Answer 25

position of gene does not change, relative association of allele does

Question 26

Less recombination frequency in genes distance

Answer 26

genes that are closer together

Question 27

Recombination frequency tool

Answer 27

used to determine distance between genes along the same chromosome

Question 28

High density linkage maps

Answer 28

identify genetic loci that are merely a few thousand base pairs apart

Question 29

GWAS

Answer 29

genome wide association study, look across entire SNP-linkage map for association between a phenotype and a mapped SNP