T15 Blood Vessels: Peripheral Circulation Flashcards
What are arteries?
carry blood away from the heart
What are capillaries?
- site of exchange of molecules and fluid between blood and tissue
- smallest blood vessels
What are veins?
carry blood toward the heart
What are elastic arteries?
- conduct blood
- diameter: 1-2.5cm (largest diameter)
What are muscular arteries?
- distribute blood
- diameter: 0.3mm-1.0cm (second largest diameter)
Order of blood vessels by diameter (smallest to largest)?
capillaries, venules, arterioles, musclar arteries, elastic arteries, veins
What are the 3 layers (tunics) of arteries?
1) tunica intima
2) tunica media
3) tunica externa
What is the lumen?
central blood-filled space of a vessel
What are the 3 parts of the tunica intima?
1) endothelium - simple squamous epithelium
2) subendothelial layer
3) internal elastic membrane
What is the tunica media composed of?
sheets of smooth muscle and elastic fibers and external elastic membrane
What does contraction of the tunica media cause?
vascoconstriction
What does relaxation of the tunica media cause?
vasodilation
What is the tunica externa composed of?
composed of collagen fibers
What are the largest arteries?
elastic arteries
What is an example of an elastic artery?
aorta and its branches
What dampens the surge of blood pressure in elastic arteries?
high elastin content
What is the Vasa vasorum in elastic arteries?
network of small blood vessels which supply walls of large elastic arteries
Where do muscular arteries lie with respect to elastic arteries?
lie distal to elastic arteries
What is a unique feature of muscular arteries?
internal and external elastic membranes that dampen the pulsatile pressure produced by the heartbeat
What is the tunica media like in musclar arteries?
tunica media = thick, w/ smooth muscle and elastin fibers
What are the smallest arteries?
arterioles
What are the 3 types of arteries?
elastic arteries, muscular arteries, arterioles
____ arterioles possess all 3 tunics?
larger
What are the 2 factors that control the diameter of arterioles?
1) local factors in the tissues
2) autonomic nervous system
What are the smallest blood vessels?
capillaries
What passes through capillaries and how?
red blood cells pass through in single file
What is the function of capillaries in the lungs?
O2 enters blood, CO2 leaves blood
What is the function of capillaries in other tissues?
O2 leaves blood, CO2 enters blood
What is the function of capillaries in the small intestines?
receive digested nutrients
What is the function of capillaries in the endocrine glands?
release or receive hormones
What is the function of capillaries in the kidneys?
remove nitrogenous wastes and other wastes
What are poorly vascularized tissues?
tendons and ligaments
What connective tissue are avascular but receive nutrients?
epithelia and cartilage = avascular and receive nutrients from nearby connective tissue
What are capillary beds?
networks of capillaries running through tissues
What is the function of precapillary sphincters?
regulate flow of blood to tissues
What do precapillary sphincters do when relaxed?
precapillary sphincters = open and blood runs through true capillaries
What do precapillary sphincters do when constricted?
precapillary sphincters = closed and blood runs through the metarteriole throughfare and bypasses true capillaries
What are the 3 types of capillaries?
1) continuous capillaries
2) fenestrated capillary
3) sinusoidal capillary
What are continuous capillaries?
most common type, least permeable type of capillaries
Where are continuous capillaries found?
found in skin, muscle, and blood brain barrier
Where is the lowest permeability continuous capillary system in?
CNS
What does the lowest permeability continuous capillary system form?
blood brain barrier
What type of junctions do capillaries have?
capillaries have complete tight junctions of endothelial cells which prevent movement through intercellular clefts
What passes through continuous capillaries and how?
Vital molecules pass through via highly selective trasnport mechanisms through endothelial cell membranes and via pinocytotic vesicles
What are continuous capillaries NOT a barrier against?
not a barrier against oxygen, carbon dioxide, and some drugs (e.g. anesthetics and anti-seizure meds) that pass through blood brain barrier
What are pericytes?
contractile cells that wrap around endothelial cells around continuous capillaries
Where are pericytes embedded?
pericytes embedded in basement membrane of endothelial cells
What is the function of pericytes?
to communicate with and help sustain endothelial cells
What are fenestrated capillaries?
large fenestrations (pores) result in increased permeability
Where are fenestrated capillaries found?
found in kidneys and small intestine
What are the most permeable capillaries?
sinusoidal capillaries
What are features of sinusoidal capillaries?
wide open intercellular clefts (gaps of unjoined membrane through which small molecules can enter and exit)
Do sinusoidal capillaries have a complete basement membrane?
no, have incomplete basement membrane
What is the diameter and physical nature of sinusoidal capillaries?
large diameter and twisted course
Where are sinusoidal capillaries found?
found in bone marrow, liver, and spleen
What do venules and veins do?
conduct blood from capillaries toward the heart
What is the blood pressue like in venules and veins in comparison to arteries?
blood pressure much lower than in arteries
What are the smallest veins called?
venules
What are the smallst venules?
postcapillary venules
Venules join to form what?
veins
What is the tunica externa like in veins?
tunica externa rich in collagenous tissue and is thickest in veins
What are 2 mechanisms to help move venous blood (against gravity)?
valves and skeletal muscle
How do valves help move venous blood?
in some veins, particularly in limbs