T Cells: Part 1

Question 1

ART components of adaptive immunity?

Answer 1

Avoid- anatomic barriers and behavior modification
Resist- reducing or eliminating pathogens
Tolerate- enhance tissues capacity to resist damage induced by pathogens

Question 2

3 characteristics of adaptive immunity?

Answer 2

Specific
Systemic
Long-lasting memory

Question 3

Timeline of adaptive immune system?

Answer 3

Slow (days to weeks)

Question 4

Components of adaptive immune system?

Answer 4

B cells/antibodies, T cells

Question 5

Describe the specificity of AI?

Answer 5

Directed against specific antigen by AG specific lymphocyte generation (B/T lymphocytes)

Question 6

Describe the systemic nature of AI?

Answer 6

targeted and can reach all parts of the body

Question 7

Describe the long term memory nature of AI?

Answer 7

Once exposed to pathogen, the animal will make an immediate and stronger response to any subsequent exposure

Question 8

Vaccines comparison to AI?

Answer 8

Induce long term memory against specific pathogens

Question 9

What are lymphocytes? T vs. B lymphocytes.

Answer 9

Slide 6

Question 10

What are naive lymphocytes?

Answer 10

Slide 7
never encountered antigens
very small, not functional
differentiate into effector and memory lymphocytes
Origin: lymphoid stem cells

Question 11

Where does the development of naive lymphocytes occur? T vs. B cells

Answer 11

Primary Lymphoid organs
T: thymus
B: bone marrow, bursa of fabricius, Peyer’s patches

Question 12

Where do naive lymphocytes respond to antigens?

Answer 12

Secondary lymphoid organs
Spleen, lymph nodes, tonsils, MALT, peyer’s patches

Question 13

How do B and T lymphocytes differ?
Structure and expression

Answer 13

Slide 9

Question 14

Function of thymic epithelial cells in naive T lymphocyte development.

Answer 14

Slide 10

Question 15

Review slide 11-14