Systemic hypertension I Flashcards
normotensive people at age 55 have what % lifetime risk for developing HTN?
90%
JNC 8 makes recommendations for BP levels to begin drug therapy depending on what factors?
age
coexisting diseases
race
how does a narrow or loose cuff affect estimation of BP?
overestimation
what is the most accurate way to measure BP (3 factors)?
- several readings
- reconfirm with 3 readings, each a week apart
- use both arms
definition: borderline HTN
BP only occasionally exceeds normal
definition: primary HTN
elevated systemic BP without known cause
definition: secondary HTN
elevated BP for which a cause can be identified (renal failure, aldosteronism)
definition: hypertensive emergency
life threatening circumstance of focal or generalized symptoms of acute, ongoing, target-oriented damage - retina / CNS, cardiac, etc
definition: malignant HTN (hypertensive retinopathy grades III and IV and severe BP elevation)
indicative of target organ damage
definition: hypertensive encephalopathy
signs and/or symptoms of cerebral edema caused by severe and/or sudden rises in BP
hypertensive retinopathy grade 1
arteriolar narrowing
hypertensive retinopathy grade 2
AV nicking
hypertensive retinopathy grade 3
hemorrhages and exudates
hypertensive retinopathy grade 4
papilledema
AV nicking
hypertensive retinopathy grade 2
arteriolar narrowing
hypertensive retinopathy grade 1
papilledema
hypertensive retinopathy grade 4
hemorrhages and exudates
hypertensive retinopathy grade 3
what is korotkoff (indirect) BP measuremet?
inflate 20 mm Hg ABOVE anticipated sBP
deflate no faster than 3 mm Hg / sec
record 1st and 5th sounds
what is the direct method of BP measurement?
intra-arterial catheter
what are the CNS consequences of systemic HTN?
- decreasing cognitive function with age
- transient ischemic attack (extracranial atherosclerosis)
- stroke, either thromboembolic or hemorrhagic
what are the renal consequences of systemic HTN?
- intraglomerular HTN results in albuminuria (glomerular leak)
- nephrosclerosis results in loss of renal concentrating ability - renal failure and eventual uremia
what is the leading cause of end stage renal disease?
systemic arterial HTN
what is considered to be a root cause of primary systemic arterial HTN?
subtle renal dysfunction
what are the EARLY cardiac consequences of systemic HTN?
increasing LV mass (thickness) resulting in loss of LV diastolic function (poor filling)
what are the CHRONIC cardiac consequences of systemic HTN?
LVH with eventual LV dilation and failure with eventual death
what are the vascular consequences of systemic HTN?
SAH is one the major risk factors for ASCVD, MI, HF, and sudden cardiac death
is heart failure a syndrome or a disease?
syndrome