Cardiomyopathies Flashcards

1
Q

definition: dilated cardiomyopathy

A

a disorder of myocardial muscle resulting in dilation and weakening of the left ventricle

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2
Q

definition: hypertrophic cardiomyopathy

A

disorders of myocardial muscle resulting in hypertrophy, left ventricular dysfunction and arrhythmias

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3
Q

definition: restrictive cardiomyopathy

A

a group of disorders resulting in excessive myocardial stiffening with resultant ventricular dysfunction

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4
Q

what is the functional classification of dilated cardiomyopathy?

A
  1. ventricular dilation and contractile dysfunction

2. most common

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5
Q

what is the functional classification of hypertrophic cardiomyopathy?

A
  1. thickened walls (symmetric or asymmetric) with preserved contractile function
  2. familial
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6
Q

what is the functional classification of restrictive cardiomyopathy?

A

impaired diastolic filling without dilation

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7
Q

what is most common cause of dilated cardiomyopathy in the US?

A

ischemic CAD

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8
Q

what is the syndrome caused by dilated cardiomyopathy?

A

heart failure

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9
Q

what are the signs and symptoms of dilated cardiomyopathy?

A

LV failure - fatigue, weakness, dyspnea, pallor, tach

RV failure - anorexia, early satiety, elevated jugular pulsations

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10
Q

where is the cardiac apex located in dilated cardiomyopathy?

A

displaced down and to the left

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11
Q

what is universally present in dilated cardiomyopathy? why?

A

S3

ventricular volume overload

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12
Q

what is the most common cause of RV failure?

A

LV failure

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13
Q

what is pulsus alternans? what is it a sign of?

A

stronger pulse every other beat

RV failure

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14
Q

what are the agents of choice for dilated cardiomyopathy?

A

ACE inhibitors

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15
Q

what is the macroscopic pathology associated with hypertrophic cardiomyopathy?

A
  1. increased myocardial mass
  2. asymmetric septal hypertrophy
  3. concentric hypertrophy
  4. apical hypertrophy
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16
Q

what is the microscopic pathology associated with hypertrophic cardiomyopathy?

A
  1. myofibrillary dysarray - whorls of deformed myocytes
  2. prominent fibrosis
  3. abnormal intramural coronaries
17
Q

what are the signs associated with hypertrophic cardiomyopathy?

A
  1. slightly displaced, bifid LV impulse
  2. bisferiens carotid pulse
  3. S4 very common
  4. systolic murmur of variable quality
18
Q

what are the ECG manifestations of hypertrophic cardiomyopathy?

A
  1. increased voltages in anterior leads
  2. ST and T changes (repolarization abn)
  3. Q waves (inferior, lateral)
  4. ventricular arrhythmias
19
Q

what test is diagnostic for hypertrophic cardiomyopathy?

A

echo

20
Q

what is the hallmark of restrictive cardiomyopathy?

A

diastolic dysfunction due to scarring or infiltration