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Pharmacology 2 > Sympathomimetics (cardiovascular) > Flashcards

Sympathomimetics (cardiovascular) Flashcards

1
Q

Suffix
Sympathomimetics (cardiovascular)

A

“ine”

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2
Q

“ine” Drug class

A

Sympathomimetics (cardiovascular)

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3
Q

Generic drug names
Sympathomimetics (cardiovascular)

A

Adrenaline (epinephrine) (cardiovascular)
Dobutamine
Dopamine
Isoprenaline
Noradrenaline (norepinephrine)

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4
Q

MOA
Sympathomimetics

A

Sympathomimetics partially or completely mimic the agonistic actions of noradrenaline or adrenaline on the alpha and/or beta adrenoreceptors. The effect of a specific agent is determined by receptor specificity, compensatory reflexes evoked and dose.

Sympathomimetics have a range of therapeutic uses, eg treating hypotension, arrhythmias, heart failure, anaphylactic reactions and bronchospasm.

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5
Q

Indication
Sympathomimetics

A

Heart Failure

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6
Q

Practice Points
Sympathomimetics

A
  • treatment with sympathomimetics is guided by haemodynamic monitoring; individualise treatment depending on clinical response
  • **use is restricted **to settings where close monitoring of arterial and venous pressure, and continuous ECG can be performed
  • prolonged use of sympathomimetics may result in diminution of therapeutic effect (down-regulation of receptors)
  • combinations of sympathomimetics may be used
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7
Q

Drug class and indication

Adrenaline (epinephrine) (cardiovascular)

A

Sympathomimetic
* Cardiac arrest
* Inotropic support in acute heart failure and cardiogenic shock, septic shock, seek specialist advice

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8
Q

Drug class and indications

Dobutamine

A

Sympathomimetic
* Inotropic support in acute heart failure, cardiogenic and septic shock
* Pharmacological stress testing of myocardial function

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9
Q

Drug class and indication

Dopamine

A

Sympathomimetic
Inotropic support in acute heart failure and cardiogenic shock due to MI, acute exacerbation of chronic heart failure

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10
Q

Drug class and indication

Noradrenaline (norepinephrine)

A

Sympathomimetic
Acute hypotension

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Pharmacology 2 (41 decks)

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