Heparins Flashcards

1
Q

Suffix
Heparins

A

“parin”

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2
Q

Drug class
“parin”

A

Heparins

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3
Q

Heparins fall under what drug class?

A

Anticoagulants

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4
Q

Generic Drug names
Heparins

A

Dalteparin
Danaparoid
Enoxaparin
Heparin
Nadroparin

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5
Q

Indication
Heparins

A

Prevention of VTE and other thromboses in surgical and high-risk medical patients (including during procedures, eg haemodialysis)
Treatment of VTE
Treatment of ACS
Treatment of peripheral arterial occlusion
Treatment of disseminated intravascular coagulation (DIC)

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6
Q

MOA
Heparins

A

Inactivate clotting factors IIa (thrombin) and Xa by binding to antithrombin III; LMWHs and danaparoid have a much greater effect on factor Xa than on thrombin.

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7
Q

Precautions
Heparins

A

Risk of bleeding
Do not use when there is risk of bleeding i.e. active bleeding, stroke.

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8
Q

Adverse effects
Heparins

A

bleeding, bruising and pain at injection site, hyperkalaemia

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9
Q

Counselling
Heparins

A

Tell your doctor immediately if you have any signs of bleeding

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10
Q

Drug class and indication

Dalteparin

A

Heparins
* * Prevention of VTE in surgical patients
* Treatment of acute DVT
* Treatment of symptomatic VTE and prevention of recurrence in solid tumour cancers
* Prevention of extracorporeal thrombosis during haemodialysis

Anticoagulant

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11
Q

Drug class and indication

Danaparoid

A

Heparins
Prevention of VTE in surgical patients

Anticoagulant

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12
Q

Drug class and indication

Enoxaparin

A

Heparins
* Prevention of VTE in surgical patients and in high-risk medical patients immobilised due to acute illness
* Treatment of venous thrombosis
* Prevention of extracorporeal thrombosis during haemodialysis
* Treatment of acute STEMI, non-STEMI and unstable angina

Anticoagulant

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13
Q

Drug class and indication

Heparin

A

Heparins
* Prevention of VTE in surgical and high-risk medical patients
* Treatment of VTE
* Treatment of ACS

Anticoagulant

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14
Q

Drug class and indication

Nadroparin

A

Heparins
* Prevention of deep vein thrombosis (DVT) in surgical patients
* Prevention of VTE in high-risk medical patients immobilised due to acute illness or in an intensive care unit
* Treatment of DVT
* Prevention of clotting during haemodialysis

Anticoagulant

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