Sympathetic Drugs Flashcards

1
Q

Epi effect

A

Beta>alpha

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2
Q

NE effect

A

Alpha1>alpha2>Beta1

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3
Q

isoproterenol effect

A

Beta1=Beta2

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4
Q

DA effect

A

D1=D2>Beta>alpha

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5
Q

Dobutamine effect

A

Beta1>Beta2,alpha

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6
Q

Phenylephrine

A

alpha1>alpha2

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7
Q

albuterol, salmeterol, terbutaline

A

beta2>beta1

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8
Q

Clonidine MOA

A

alpha2-agonist

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9
Q

alpha-methyldopa MOA

A

alpha2-agonist

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10
Q

Phenoxybenzamine MOA and use

A

alpha-blocker, irreversible, before pheo surgery

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11
Q

Phentolamine MOA and use

A

alpha-blocker, give to MAOI patients

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12
Q

Prazosin, terazosin, doxazosin, tamsulosin

A

alpha1 selective blocker (end in -osin)

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13
Q

Mirtazapine MOA

A

alpha2 selective blocker

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14
Q

What class of antiarrhythmics are beta-blockers

A

class II

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15
Q

Beta1-selective antagonists

A

From A to M in alphabet: acebutolol, atenolol, betaxolol, esmolol, metoprolol (B1 is first half of alphabet)

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16
Q

Nonselective beta antagonists

A

Go N to Z: nadolol, pindolol (partial agonist), propranolol, timidol

17
Q

Nonselective alpha and beta-antagonists

A

Modified endings (not -olol), carvedilol, labetalol

18
Q

Nebivolol

A

NO synthase activity through Beta3. Cardiac selective beta-1 as well.