Antineoplastics Flashcards
1
Q
Mitosis inhibitor
A
Vinca alkaloids and Taxols
2
Q
DNA synthesis inhibitor
A
Antimetabolites and EToposide
3
Q
G2 inhibitor
A
Etoposide and Bleomycin
4
Q
Nucleotide synthesis inhibitor
A
MTX, 5-FU block thymidine synthesis
6-MP dec. purine synthesis
5
Q
Alkylating agents
A
cisplatin: cross-link DNA
6
Q
DNA intercalators
A
Dactinomycin, doxorubicin
7
Q
Etoposide MOA
A
inhibits topoisomerase II
8
Q
Vinca alkaloids MOA
A
inhibits microtubule formation
9
Q
Paclitaxel MOA
A
inhibits microtubule disassembly