Antineoplastics Flashcards

1
Q

Mitosis inhibitor

A

Vinca alkaloids and Taxols

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2
Q

DNA synthesis inhibitor

A

Antimetabolites and EToposide

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3
Q

G2 inhibitor

A

Etoposide and Bleomycin

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4
Q

Nucleotide synthesis inhibitor

A

MTX, 5-FU block thymidine synthesis

6-MP dec. purine synthesis

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5
Q

Alkylating agents

A

cisplatin: cross-link DNA

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6
Q

DNA intercalators

A

Dactinomycin, doxorubicin

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7
Q

Etoposide MOA

A

inhibits topoisomerase II

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8
Q

Vinca alkaloids MOA

A

inhibits microtubule formation

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9
Q

Paclitaxel MOA

A

inhibits microtubule disassembly

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